Effects of repeated doses of pseudoephedrine on blood pressure and plasma catecholamines in normal subjects and in patients with phaeochromocytoma.

Author: BachmannA W, BallantineD M, GordonR D

Paper Details 
Original Abstract of the Article :
1. Increases in blood pressure (BP) and in plasma noradrenaline concentration (NA) were observed after two doses of a non-prescription decongestant containing pseudoephedrine (PE) in two of three patients with phaeochromocytoma, before but not after removal of the tumour. The pressor response was te...See full text at original site
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引用元:
https://doi.org/10.1111/j.1440-1681.1992.tb00453.x

データ提供:米国国立医学図書館(NLM)

Pseudoephedrine: A Hidden Risk in Hypertension

Pseudoephedrine is a common over-the-counter decongestant found in many cold and allergy medications. This study investigates the potential effects of pseudoephedrine on blood pressure and plasma catecholamines (hormones that regulate blood pressure and heart rate) in both healthy individuals and patients with phaeochromocytoma, a rare tumor that produces excess catecholamines.

A Hidden Danger in the Desert

The study found that pseudoephedrine can cause a significant increase in blood pressure and plasma noradrenaline levels, particularly in patients with phaeochromocytoma. This finding suggests that pseudoephedrine can be dangerous for individuals with hypertension, especially those with underlying conditions that affect catecholamine production. This highlights the importance of carefully considering the potential risks of over-the-counter medications, even for seemingly harmless conditions like colds and allergies.

Navigating the Desert of Medication Safety

This study is a valuable reminder that seemingly innocuous medications can have hidden risks. It's like navigating a desert; what appears to be a safe and familiar path can be fraught with danger. This research emphasizes the importance of carefully considering medication history, medical conditions, and potential interactions before using any medication, even over-the-counter products.

Dr. Camel's Conclusion

This study reminds us that even common medications can have hidden risks. It's like a desert oasis; while it may offer temporary relief, there might be hidden dangers lurking beneath the surface. This research encourages us to be cautious about medication use, especially for individuals with specific medical conditions, and to consult with healthcare professionals for personalized guidance.

Date :
  1. Date Completed 1992-10-15
  2. Date Revised 2019-08-24
Further Info :

Pubmed ID

1521358

DOI: Digital Object Identifier

10.1111/j.1440-1681.1992.tb00453.x

Related Literature

SNS
PICO Info
in preparation
Languages

English

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