Idarubicin administered during pregnancy: its effects on the fetus.

Author: KoyamaMasayasu, MatsuoKoji, MurataYuji, ShimoyaKoichiro, UedaShuji, WadaKazuko

Paper Details 
Original Abstract of the Article :
Acute myeloblastic leukemia, subtype M1, was diagnosed in a 39-year-old G2P1 Japanese woman at 21 weeks' gestation. Remission-induction polychemotherapy, including daunorubicin, performed for one cycle, did not lead to remission. Second-line chemotherapy, including idarubicin, performed for one cycl...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/15256824

データ提供:米国国立医学図書館(NLM)

Idarubicin: A Double-Edged Sword in Pregnancy

Navigating the complexities of pregnancy while battling cancer is a daunting challenge for both mother and child. This research investigates the effects of idarubicin, a chemotherapy drug, on a pregnant woman diagnosed with acute myeloblastic leukemia. The authors describe a case study of a woman who received idarubicin during her third trimester, highlighting the potential risks to the fetus. Although the newborn exhibited signs of transient myelosuppression, hepatopathy, and elevated creatine kinase, the mother achieved complete remission. This case study raises crucial questions about the risks and benefits of using idarubicin during pregnancy and emphasizes the need for careful consideration and close monitoring of both mother and fetus.

Walking the Tightrope of Cancer Treatment During Pregnancy

This case study serves as a reminder of the complex challenges faced by pregnant women diagnosed with cancer. While idarubicin proved effective in achieving remission for the mother, it also led to complications for the fetus. This highlights the need for meticulous risk-benefit assessments and close monitoring of both mother and fetus during chemotherapy treatment.

A Balancing Act of Motherhood and Treatment

This study highlights the delicate balancing act that pregnant women with cancer must navigate. It's crucial to consult with a specialist who can provide individualized care and explain the potential risks and benefits of treatment options. Open communication between the patient and her medical team is paramount in making informed decisions that prioritize the health and well-being of both mother and child.

Dr.Camel's Conclusion

This research offers a glimpse into the difficult decisions that arise when cancer strikes during pregnancy. The authors emphasize the need for careful consideration of the risks and benefits of chemotherapy treatment for both mother and child. It's a testament to the resilience of both mothers and medical professionals in facing these challenges head-on.

Date :
  1. Date Completed 2005-04-11
  2. Date Revised 2022-03-31
Further Info :

Pubmed ID

15256824

DOI: Digital Object Identifier

79814

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English

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