Dipyridamole and headache--a pilot study of initial dose titration.

Author: HustedSteen, LindgrenArne, StaafGert, ZieglerBirgitte

Paper Details 
Original Abstract of the Article :
Headache is reported by about one third of patients using dipyridamole (DP) after stroke or TIA. No study has systematically examined if initial dipyridamole titration may affect this headache. We therefore randomised patients to (1) standard aspirin and dipyridamole treatment b.i.d. for 2 weeks or ...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/15337620

データ提供:米国国立医学図書館(NLM)

Dipyridamole: Navigating the Side Effects

Dipyridamole (DP) is a medication often used to prevent blood clots after stroke or transient ischemic attack (TIA). One common side effect of DP is headache. This study explores the potential of initial dose titration to minimize headache and improve patient compliance.

Reducing Headache: A Gradual Approach

The study found that initial dose titration of DP, starting with a lower dose and gradually increasing it, may be associated with a lower incidence and severity of headache compared to starting with the standard dose. While the study was small and the differences were not statistically significant, the findings suggest that titration could be a helpful strategy for managing this common side effect.

Improving Compliance: A Key to Effective Treatment

The study highlights the importance of managing side effects to improve patient compliance with medication. Headache can be a significant deterrent to taking DP, so minimizing this side effect is crucial for ensuring that patients receive the full benefits of this important medication.

Dr.Camel's Conclusion

The study provides preliminary evidence suggesting that initial dose titration of dipyridamole could be a useful strategy for managing headache, a common side effect of this medication. While larger studies are needed to confirm these findings, the study highlights the importance of individualizing treatment approaches to optimize patient outcomes and improve compliance with medication.

Date :
  1. Date Completed 2004-11-15
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

15337620

DOI: Digital Object Identifier

S0022510X04001704

Related Literature

SNS
PICO Info
in preparation
Languages

English

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