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Treatment of primary acute myeloid leukemia: results of a prospective multicenter trial including high-dose cytarabine or stem cell transplantation as post-remission strategy.

Author: , BargayJoan, BerlangaJoan, BrunetSalut, BuenoJavier, EsteveJordi, GranenaAlbert, GuardiaRamon, JuliáAntoni, MartíJosep M, MontserratEmili, RiberaJosep M, SierraJorge

Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

High-dose cytarabine is a good option for patients with t(8;21) acute myeloid leukemia. Autologous and allogeneic stem cell transplantation lead to similar leukemia-free survival in patients under 50 years old, but autologous SCT results are poor in older patients.
Paper Details　
Original Abstract of the Article :
BACKGROUND AND OBJECTIVES: To evaluate a regimen of induction and consolidation chemotherapy, followed by a post-remission therapy which depended on age and cytogenetics, in patients with primary acute myeloid leukemia. DESIGN AND METHODS: Two hundred patients up to 60 years old received idarubicin...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/15339677

データ提供：米国国立医学図書館（NLM）
in preparation
Date :
  1. Date Completed 2006-03-08
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

15339677

DOI: Digital Object Identifier

15339677

SNS
PICO Info
in preparation
Languages

English

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