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A randomized trial of nortriptyline combined with transdermal nicotine for smoking cessation.
Author: FryerGeorge E, KickSteven, MiyoshiThomas, ProchazkaAllan V, SteinbrunnConnie
Original Abstract of the Article :
BACKGROUND: Smoking cessation rates with current therapy are suboptimal. Tricyclic antidepressants improve cessation rates. We hypothesized that addition of nortriptyline hydrochloride to transdermal nicotine would enhance cessation rates. METHODS: We conducted a randomized, double-blind, placebo-c...See full text at original site
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引用元:
https://doi.org/10.1001/archinte.164.20.2229
データ提供:米国国立医学図書館(NLM)
A Quest for Better Smoke-Free Lives: A Randomized Trial Combining Nortriptyline and Nicotine
This study delves into the fascinating world of [smoking cessation research]. Like a desert traveler seeking a cool oasis, researchers in this study were determined to find a more effective way to help smokers break free from their habit. They employed a [randomized, double-blind, placebo-controlled trial] to investigate the effectiveness of combining [nortriptyline hydrochloride] and [transdermal nicotine] for smoking cessation. They wanted to see if this combination would be more successful than the current standard treatments.
Their research revealed a [slightly increased cessation rate] at six months for those receiving the combination therapy compared to those receiving a placebo. However, the difference was not statistically significant, indicating that this combination therapy may not be a game-changer for all smokers.
A Twinkle in the Smoke-Free Desert: Some Hope, But More Research Needed
While the results were promising, the authors acknowledge that further investigation is necessary to determine the true potential of this combination therapy. They also highlight the importance of considering the potential side effects of [nortriptyline hydrochloride] and the need for individualized treatment approaches.
Navigating the Smoker's Path: A Multifaceted Approach
This research reminds us that quitting smoking is a complex journey. There is no one-size-fits-all solution, and what works for one smoker may not work for another. A holistic approach that considers both behavioral interventions and medication options may be the key to achieving long-term success.
Dr. Camel's Conclusion
This study is like a desert wind blowing a new direction, suggesting that combining medications might be a promising avenue for helping smokers quit. However, the wind is still fickle and more research is needed to see if this approach can truly offer a lasting solution to the challenges of smoking cessation.
Date :
- Date Completed 2004-12-02
- Date Revised 2015-11-19
Further Info :
Related Literature
English
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