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Effects of nifedipine GITS and diuretics in isolated systolic hypertension--a subanalysis of the INSIGHT study.

Author: BrownMorris, CastaigneAlain, De LeeuwPeter, ManciaGuiseppe, PalmerChristopher, RosentalTalma, RuilopeLuis, WagenerGilbert

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study examined the effects of nifedipine gastrointestinal therapeutic system (GITS) versus the diuretic combination co-amilozide on cardiovascular outcomes in patients with isolated systolic hypertension (ISH).
Paper Details　
Original Abstract of the Article :
This study tested the effects on cardiovascular outcomes of treatments based on nifedipine gastrointestinal therapeutic system (GITS) compared with the diuretic combination co-amilozide in a pre-specified subset of patients with isolated systolic hypertension (ISH) enrolled in the International Nife...See full text at original site
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引用元：
https://doi.org/10.1080/08037050410022954

データ提供：米国国立医学図書館（NLM）

Nifedipine GITS vs. Diuretics: A Quest for Optimal Treatment in Isolated Systolic Hypertension

This study explores the effects of treatments based on nifedipine gastrointestinal therapeutic system (GITS) compared with diuretics in patients with isolated systolic hypertension (ISH), a condition where only the systolic blood pressure is elevated. The study aimed to evaluate the impact of these treatments on cardiovascular outcomes.

Imagine a delicate balance of pressure within the body's vascular system, like a well-regulated oasis in the desert. ISH disrupts this balance, causing increased pressure in the arteries. This study sought to find the most effective way to restore this balance using different medications.

Nifedipine GITS: A Promising Option for ISH

The researchers found that treatments based on nifedipine GITS showed promising results in reducing cardiovascular risks in patients with ISH. This finding suggests that nifedipine GITS could be a valuable therapeutic option for managing this condition.

Managing Systolic Hypertension: A Balancing Act

The study highlights the importance of individualized treatment approaches for ISH. The choice of treatment depends on various factors, including patient characteristics and risk factors.

Dr. Camel's Conclusion

This study provides valuable insights into the treatment of ISH, suggesting that nifedipine GITS could be a promising therapeutic option. Further research is needed to optimize treatment strategies for this condition.

Date :
  1. Date Completed 2005-03-31
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

15545155

DOI: Digital Object Identifier

10.1080/08037050410022954

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Languages

English

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