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A comparative study: the efficacy of liquid paraffin and lactulose in management of chronic functional constipation.

Author: AkyildizBasak, PolatTugçin Bora, UrganciNafiye

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Liquid paraffin is more effective than lactulose in treating children with constipation, with faster response times and fewer side effects. However, compliance rates were lower for both drugs due to side effects and poor symptom control.
Paper Details　
Original Abstract of the Article :
OBJECTIVES: To determine and compare efficacy, safety and optimal dose of two laxatives, liquid paraffin and lactulose, in 40 children with chronic functional constipation. METHODS: A total of 20 children were treated with liquid paraffin and 20 with lactulose for 8 weeks and at an initial dose of ...See full text at original site
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引用元：
https://doi.org/10.1111/j.1442-200x.2004.02001.x

データ提供：米国国立医学図書館（NLM）

Constipation in Children: A Desert of Discomfort

Constipation is a common problem, particularly in children. This study compares the effectiveness of two laxatives, liquid paraffin and lactulose, in treating chronic functional constipation in children. The authors conducted a randomized, controlled trial involving 40 children with constipation to assess the efficacy, safety, and optimal dosage of these medications.

A Comparison of Treatments

The study found that liquid paraffin was more effective than lactulose in improving stool consistency and frequency in children with constipation. Liquid paraffin also led to better compliance rates, suggesting it might be a preferable treatment option. The authors highlight the importance of carefully considering the individual needs of each child when choosing a treatment strategy.

Finding Relief in the Desert

This study offers valuable insights into the treatment of childhood constipation, highlighting the potential benefits of liquid paraffin. It's like finding a refreshing oasis in the desert of constipation, providing relief and improved quality of life for children struggling with this condition.

Dr. Camel's Conclusion

This study offers helpful guidance for navigating the often uncomfortable terrain of childhood constipation. Liquid paraffin, like a trusty camel, can help children find their way to a more comfortable digestive journey.

Date :
  1. Date Completed 2005-05-12
  2. Date Revised 2016-05-11
Further Info :

Pubmed ID

15693860

DOI: Digital Object Identifier

10.1111/j.1442-200x.2004.02001.x

Related Literature

Article Analysis
・Side Effects of lactulose
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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