Magnetic resonance imaging of the spine and the sacroiliac joints in ankylosing spondylitis and undifferentiated spondyloarthritis during treatment with etanercept.

Author: BaraliakosX, BrandtJ, BraunJ, ListingJ, RudwaleitM, SieperJ

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To assess the changes in inflammatory lesions of the spine and the sacroiliac (SI) joints as detected by magnetic resonance imaging (MRI) in patients with ankylosing spondylitis (AS) and undifferentiated spondyloarthritis (uSpA) with predominant axial symptoms during treatment with etaner...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1755637/

データ提供:米国国立医学図書館(NLM)

Etanercept: A Beacon of Hope in the Desert of Ankylosing Spondylitis

Ankylosing spondylitis (AS) and undifferentiated spondyloarthritis (uSpA), like persistent desert winds, cause chronic inflammation and pain. This study investigates the effects of etanercept, a tumor necrosis factor (TNF) inhibitor, on the inflammatory lesions of the spine and sacroiliac (SI) joints in patients with AS and uSpA.

Etanercept: A Potential Oasis in the Desert of Inflammation?

Using magnetic resonance imaging (MRI), researchers observed a significant regression of spinal inflammation in patients treated with etanercept, like finding a refreshing spring in the midst of a desert. The study found that etanercept significantly reduced active spinal changes after 6 weeks and 24 weeks of treatment, suggesting its potential to suppress inflammation in AS and uSpA.

Health Implications and Application

These findings, like a beacon of hope in the desert of chronic pain, suggest that etanercept may offer an effective treatment option for AS and uSpA. However, further research is needed to explore its long-term effects and evaluate its impact on the progression of chronic spinal changes. Further studies are necessary to understand the full implications of this treatment and to optimize its use in clinical practice.

Dr.Camel's Conclusion

Navigating the desert of AS and uSpA can be a challenging journey, filled with pain and discomfort. This study offers a glimmer of hope, suggesting that etanercept may provide a safe and effective treatment option for these chronic inflammatory conditions. However, the desert of medical research is vast, and we must continue our quest for deeper understanding and more effective therapies for these debilitating diseases.

Date :
  1. Date Completed 2005-10-06
  2. Date Revised 2022-04-09
Further Info :

Pubmed ID

15778243

DOI: Digital Object Identifier

PMC1755637

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.