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Meta-analysis: pharmacologic treatment of obesity.
Author: ArterburnDavid, HiltonLara, LiZhaoping, MaglioneMargaret, MojicaWalter, MortonSally C, ShekellePaul G, ShugarmanLisa R, SolomonVanessa, SuttorpMarika, TuWenli
Original Abstract of the Article :
BACKGROUND: In response to the increase in obesity, pharmacologic treatments for weight loss have become more numerous and more commonly used. PURPOSE: To assess the efficacy and safety of weight loss medications approved by the U.S. Food and Drug Administration and other medications that have been...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.7326/0003-4819-142-7-200504050-00012
データ提供:米国国立医学図書館(NLM)
A Meta-Analysis of Pharmacologic Treatments for Obesity
The quest to combat the global obesity epidemic is an ongoing battle. This research, like a compass guiding through a vast desert of treatment options, provides a comprehensive overview of the efficacy and safety of pharmacologic treatments for weight loss. The authors meticulously analyzed data from numerous clinical trials, evaluating the effectiveness of various weight-loss medications. Their findings reveal that certain medications, such as sibutramine and orlistat, can contribute to modest weight loss when combined with lifestyle changes, including a healthy diet. However, it's important to note that these medications are not a magic bullet, and they come with potential side effects.
A Modest Success: Weight Loss and Side Effects
The meta-analysis, a meticulous analysis of multiple studies, showed that certain medications led to a modest weight loss compared to placebo. For example, sibutramine was associated with an average weight loss of 4.45 kg after 12 months. However, the study also highlighted the importance of considering potential side effects associated with these medications. It’s like a camel traversing a desert – while there may be a path leading to a destination, it’s essential to be aware of the potential obstacles and hazards along the way.
Balancing Benefits and Risks
The findings underscore the need for a balanced approach when considering pharmacologic treatments for obesity. While these medications can offer a potential advantage, it’s crucial to weigh their benefits against their potential risks and to consult with a healthcare professional before making any decisions. It’s like navigating a desert – understanding the terrain and its challenges is essential for a successful journey.
Dr.Camel's Conclusion
This research provides valuable insights into the effectiveness and safety of pharmacologic weight-loss treatments. While these medications can offer modest benefits, they should be considered in conjunction with lifestyle modifications. It's like finding a well in the desert – it can provide temporary relief, but it's not a permanent solution.
Date :
- Date Completed 2005-04-11
- Date Revised 2022-03-21
Further Info :
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