Meta-analysis: pharmacologic treatment of obesity.

Author: ArterburnDavid, HiltonLara, LiZhaoping, MaglioneMargaret, MojicaWalter, MortonSally C, ShekellePaul G, ShugarmanLisa R, SolomonVanessa, SuttorpMarika, TuWenli

Paper Details 
Original Abstract of the Article :
BACKGROUND: In response to the increase in obesity, pharmacologic treatments for weight loss have become more numerous and more commonly used. PURPOSE: To assess the efficacy and safety of weight loss medications approved by the U.S. Food and Drug Administration and other medications that have been...See full text at original site
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引用元:
https://doi.org/10.7326/0003-4819-142-7-200504050-00012

データ提供:米国国立医学図書館(NLM)

A Meta-Analysis of Pharmacologic Treatments for Obesity

The quest to combat the global obesity epidemic is an ongoing battle. This research, like a compass guiding through a vast desert of treatment options, provides a comprehensive overview of the efficacy and safety of pharmacologic treatments for weight loss. The authors meticulously analyzed data from numerous clinical trials, evaluating the effectiveness of various weight-loss medications. Their findings reveal that certain medications, such as sibutramine and orlistat, can contribute to modest weight loss when combined with lifestyle changes, including a healthy diet. However, it's important to note that these medications are not a magic bullet, and they come with potential side effects.

A Modest Success: Weight Loss and Side Effects

The meta-analysis, a meticulous analysis of multiple studies, showed that certain medications led to a modest weight loss compared to placebo. For example, sibutramine was associated with an average weight loss of 4.45 kg after 12 months. However, the study also highlighted the importance of considering potential side effects associated with these medications. It’s like a camel traversing a desert – while there may be a path leading to a destination, it’s essential to be aware of the potential obstacles and hazards along the way.

Balancing Benefits and Risks

The findings underscore the need for a balanced approach when considering pharmacologic treatments for obesity. While these medications can offer a potential advantage, it’s crucial to weigh their benefits against their potential risks and to consult with a healthcare professional before making any decisions. It’s like navigating a desert – understanding the terrain and its challenges is essential for a successful journey.

Dr.Camel's Conclusion

This research provides valuable insights into the effectiveness and safety of pharmacologic weight-loss treatments. While these medications can offer modest benefits, they should be considered in conjunction with lifestyle modifications. It's like finding a well in the desert – it can provide temporary relief, but it's not a permanent solution.

Date :
  1. Date Completed 2005-04-11
  2. Date Revised 2022-03-21
Further Info :

Pubmed ID

15809465

DOI: Digital Object Identifier

10.7326/0003-4819-142-7-200504050-00012

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PICO Info
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Languages

English

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