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Acute nateglinide administration in subjects with type 2 diabetes: effects on postprandial metabolism, coagulation, and fibrinolysis.

Author: AnastasopoulouI, BoutatiE, KarafoullidouA, KarambakalisN, KatsilambrosN, KyriakiD, LouridaE, PereaD, PerreaD, RaptisS A, TentolourisN, TselepisA D, TsoukalaC

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

A single dose of nateglinide reduced postprandial triglyceridaemia and improved coagulation in patients with type 2 diabetes.
Paper Details　
Original Abstract of the Article :
Postprandial glycaemia and lipaemia are known risk factors for atherosclerosis in type 2 diabetes. Coagulation activation in the postprandial state also contributes to acceleration of atherosclerosis. Nateglinide is effective in reducing postprandial glycaemia. Its effect on glycaemia may also be be...See full text at original site
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引用元：
https://doi.org/10.1016/j.numecd.2004.06.002

データ提供：米国国立医学図書館（NLM）

Nateglinide's Impact on Postprandial Metabolism in Type 2 Diabetes

This study investigates the effects of nateglinide, a medication used to manage type 2 diabetes, on postprandial metabolism, coagulation, and fibrinolysis. It’s like examining the intricate interactions of a desert ecosystem, where every element plays a role in maintaining balance. The study focuses on the impact of a single dose of nateglinide on postprandial glycemia, triglyceridemia, coagulation, and fibrinolysis, all key factors associated with the development of atherosclerosis in type 2 diabetes.

Nateglinide's Benefits in Postprandial Metabolism

The study found that a single dose of nateglinide effectively reduced postprandial glycemia, triglyceridemia, and coagulation. It’s like a calming oasis in the midst of a turbulent desert, offering a sense of relief and stability. These findings suggest that nateglinide may have a beneficial impact on cardiovascular health in type 2 diabetes patients by reducing the risk of atherosclerosis.

Implications for Type 2 Diabetes Management

This study provides valuable insights into the potential benefits of nateglinide in managing type 2 diabetes. It’s like discovering a hidden spring of water in the desert, providing a source of refreshment and nourishment. The study suggests that nateglinide could be a valuable tool for improving postprandial metabolic control and reducing the risk of cardiovascular complications in type 2 diabetes patients.

Dr.Camel's Conclusion

This study provides a deeper understanding of the effects of nateglinide on postprandial metabolism in type 2 diabetes. It’s like a careful exploration of a desert landscape, revealing the intricate connections between diet, medication, and health outcomes. The findings suggest that nateglinide may offer a promising approach to improving metabolic control and reducing the risk of cardiovascular complications in individuals with type 2 diabetes.

Date :
  1. Date Completed 2005-11-04
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

15871845

DOI: Digital Object Identifier

10.1016/j.numecd.2004.06.002

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Languages

English

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