Paper Details

  1. Home
  2. Paper Details

Reye's syndrome developing in an infant on treatment of Kawasaki syndrome.

Author: ChenChong-Ming, ChenHuey-Ling, HwuWuh-Liang, LeePing-Ing, MaChun-Yi, WeiChih-Ming

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Aspirin is commonly used as an anti-inflammatory therapy for Kawasaki syndrome. Early initiation with high dose aspirin (80 to > 100 mg/kg per day), followed by low-dose therapy at the afebrile stage, has been often used to reduce morbidity and mortality in coronary complications. We report a 10-month-old infant who was diagnosed with Kawasaki syndrome. Sudden onset of poor activity, poor appetite, lethargy, tachycardia, tachypnea, hepatomegaly, increased AST/ALT, coagulopathy and hyperammonemia developed 3 days after the high-dose aspirin therapy. His histopathological and ultrastructural findings from the liver biopsy were compatible with Reye's syndrome. He recovered completely, and there was no recurrence.
Paper Details　
Original Abstract of the Article :
Aspirin is commonly used as an anti-inflammatory therapy for Kawasaki syndrome. Early initiation with high dose aspirin (80 to > 100 mg/kg per day), followed by low-dose therapy at the afebrile stage, has been often used to reduce morbidity and mortality in coronary complications. We report a 10-mon...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1111/j.1440-1754.2005.00617.x

データ提供：米国国立医学図書館（NLM）

Reye's Syndrome: A Rare But Serious Complication

Aspirin is commonly used to treat Kawasaki syndrome, a rare childhood disease that can affect the heart and blood vessels. However, this study highlights a rare but serious complication of aspirin therapy: Reye's syndrome, a potentially life-threatening condition that affects the liver and brain.

A Case of Unexpected Illness

A 10-month-old infant diagnosed with Kawasaki syndrome developed symptoms of Reye's syndrome three days after starting high-dose aspirin therapy. The infant recovered fully, but this case serves as a reminder of the potential risks associated with aspirin therapy in children with Kawasaki syndrome.

Navigating the Desert of Medical Risks

This case emphasizes the importance of careful monitoring and prompt intervention when treating children with Kawasaki syndrome. It's like navigating a vast desert, where unexpected storms can arise. Early recognition and appropriate management are critical to minimizing the risk of complications like Reye's syndrome.

Dr.Camel's Conclusion

This case study underscores the importance of careful consideration of drug interactions and potential complications in pediatric patients. While aspirin is a widely used medication, it's crucial to be aware of its potential risks, particularly in cases like Kawasaki syndrome, and to diligently monitor patients for any signs of complications.

Date :
  1. Date Completed 2005-10-25
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

15953335

DOI: Digital Object Identifier

10.1111/j.1440-1754.2005.00617.x

Related Literature

Article Analysis
・Effective treatment of reye syndrome
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.