Tapering dose of inhaled budesonide in subjects with mild-to-moderate persistent asthma treated with montelukast: a 16-week single-blind randomized study.

Author: CastronuovoMarco, D'OrazioNicolantonio, Di IlioCarmine, RiccioniGraziano, VecchiaRosanna Della

Paper Details 
Original Abstract of the Article :
Pharmacological therapy with inhaled steroids (IS) is currently considered the gold-standard of treatment for mild-persistent asthma. Leukotriene receptor antagonist drugs (LTRAs) play an important role associated with IS, allowing dose tapering and maintaining control of asthma symptoms. The aim of...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/16081585

データ提供:米国国立医学図書館(NLM)

Tapering Inhaled Budesonide: A Study of Asthma Management

Asthma, a chronic lung disease characterized by inflammation and airway narrowing, can significantly impact quality of life. Inhaled corticosteroids (ICS) are a mainstay of asthma treatment, but prolonged use can lead to side effects. This study investigates the potential for reducing the dose of inhaled budesonide (BUD), a commonly used ICS, in patients with mild-to-moderate persistent asthma while maintaining disease control. The authors compared the effectiveness of montelukast (MON), a leukotriene receptor antagonist, in combination with BUD, to BUD alone in tapering the inhaled dose of BUD over a 16-week period.

Montelukast: A Potential Aid in Asthma Management

The study found that in patients with mild-to-moderate persistent asthma, MON therapy was effective in allowing tapering of the inhaled dose of BUD without compromising asthma control. This finding suggests that MON may be a valuable tool for managing asthma and reducing the need for high-dose ICS, which can have unwanted side effects.

A More Personalized Approach to Asthma Management

This study highlights the importance of a more personalized approach to asthma management. It underscores the need to consider individual patient factors, such as the severity of their asthma, their response to medication, and their risk of side effects, when making treatment decisions. It reminds us that the journey to effective asthma control, like a camel's trek across the desert, can be unique for each individual and require a tailored approach to achieve success.

Dr. Camel's Conclusion

This study offers valuable insights into the management of asthma, reminding us that even the most effective treatments can have potential downsides. It suggests that combining medications, like a camel strategically using its various adaptations to navigate the desert, can lead to more personalized and effective care. The goal is to help patients achieve their optimal health and well-being, navigating the terrain of chronic illness with as much comfort and success as possible.

Date :
  1. Date Completed 2006-12-21
  2. Date Revised 2021-12-03
Further Info :

Pubmed ID

16081585

DOI: Digital Object Identifier

35/3/285

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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