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Nortriptyline for smoking cessation: a review.

Author: HughesJohn R, LancasterTim, SteadLindsay F

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This paper reviews the efficacy of nortriptyline for smoking cessation. The study found that nortriptyline doubles quit rates, with a magnitude of effect similar to bupropion and nicotine replacement therapies. However, the potential for serious side effects in healthy smokers remains unclear and further research is needed.
Paper Details　
Original Abstract of the Article :
This article reviews the efficacy of nortriptyline for smoking cessation based on a meta-analysis of the Cochrane Library. Six placebo-controlled trials have shown nortriptyline (75-100 mg) doubles quit rates (OR = 2.1). Between 4% and 12% of smokers dropped out because of adverse events, but no ser...See full text at original site
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引用元：
https://doi.org/10.1080/14622200500185298

データ提供：米国国立医学図書館（NLM）

Nortriptyline: A Potential Ally in Smoking Cessation

The struggle to quit smoking is a common challenge faced by millions worldwide. This study, like a desert explorer searching for a life-giving spring, explores the potential of nortriptyline, a medication traditionally used for depression, as a smoking cessation aid. The researchers conducted a comprehensive meta-analysis of existing studies, examining the effectiveness and safety of nortriptyline in helping smokers quit. Their findings suggest that nortriptyline could offer a valuable tool for those seeking to break free from the chains of nicotine addiction.

A Doubled Chance of Quitting: Nortriptyline Shows Promise

The study revealed that nortriptyline doubles the quit rates compared to placebo, offering a significant advantage for smokers seeking to break free from their addiction. It's like discovering a hidden oasis in the desert of addiction, providing a source of strength and support for those seeking to overcome their cravings. The researchers also found that nortriptyline was generally well-tolerated, with few serious adverse events reported.

Breaking Free From Nicotine: A Multifaceted Approach

This study highlights the potential of nortriptyline as an effective smoking cessation aid, providing an additional weapon in the arsenal for those seeking to quit. It's like discovering a new route through the desert, offering a more effective and comfortable journey toward freedom from nicotine addiction. The researchers emphasize the need for further studies to confirm its safety and efficacy, but their findings are promising.

Dr.Camel's Conclusion

This study sheds light on the potential of nortriptyline as a smoking cessation aid, offering a new path toward freedom from nicotine addiction. It's like finding a hidden oasis in the desert, providing a source of hope and support for those seeking to break free from the grip of this powerful habit. The researchers' findings highlight the need for further research, but they offer a promising avenue for exploring new ways to help smokers quit.

Date :
  1. Date Completed 2006-01-17
  2. Date Revised 2017-11-16
Further Info :

Pubmed ID

16085520

DOI: Digital Object Identifier

10.1080/14622200500185298

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Article Analysis
・Side Effects of nortriptyline
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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