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The role of corticosteroids in chronic obstructive pulmonary disease.

Author: CalverleyPeter M A

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This paper reviews the use of corticosteroids for managing COPD. The authors discuss the different forms of corticosteroids, their efficacy, and side effects. Oral corticosteroids, while effective for resolving exacerbations, can lead to worse mortality and myopathy. Inhaled corticosteroids, although safer, can cause candidiasis, hoarseness, and skin bruising. Inhaled corticosteroids are most effective when combined with a long-acting beta-agonist, especially in patients with severe disease.
Paper Details　
Original Abstract of the Article :
Oral corticosteroids are powerful relatively nonspecific antiinflammatory agents with a range of well-characterized side effects. There is good evidence to show that they accelerate the rate of resolution of exacerbations of COPD and relapse is less likely if patients receive these drugs. Maintenanc...See full text at original site
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引用元：
https://doi.org/10.1055/s-2005-869542

データ提供：米国国立医学図書館（NLM）

Navigating the Desert of Chronic Obstructive Pulmonary Disease (COPD) Treatment: The Role of Corticosteroids

Chronic obstructive pulmonary disease (COPD) is a complex and debilitating condition that affects the lungs, making it difficult to breathe. This research explores the role of corticosteroids in managing COPD, focusing on the benefits and risks of both oral and inhaled corticosteroids. The authors discuss the evidence for the use of corticosteroids in acute exacerbations, maintenance therapy, and the potential impact on lung function and health status.

This research, like a seasoned traveler traversing the vast desert of COPD, seeks to find effective and safe ways to manage this challenging condition. It’s like a search for a hidden oasis of knowledge that can lead to improved treatment strategies.

Corticosteroids: A Powerful Tool in the COPD Treatment Arsenal

The study reveals that corticosteroids play a significant role in managing COPD, particularly in accelerating the resolution of exacerbations and reducing the frequency of relapses. However, the research highlights the potential risks associated with oral corticosteroids, such as increased mortality and skeletal muscle myopathy. Inhaled corticosteroids, while less potent, offer a safer alternative, effectively reducing exacerbations and improving lung function in patients with moderate to severe COPD.

Finding Relief in the Desert of COPD: A Balanced Approach

This research underscores the importance of a balanced approach to using corticosteroids in COPD. While they offer significant benefits in managing exacerbations and improving lung function, it’s crucial to consider the potential risks and select the most appropriate form of administration based on individual patient needs.

Dr.Camel's Conclusion

This research provides a comprehensive overview of the role of corticosteroids in managing COPD. It’s like a guide through the desert of COPD treatment, highlighting the benefits and risks of these powerful medications. By carefully weighing the potential benefits and risks, healthcare providers can make informed decisions to optimize the use of corticosteroids in managing this challenging condition.

Date :
  1. Date Completed 2005-09-08
  2. Date Revised 2006-11-15
Further Info :

Pubmed ID

16088440

DOI: Digital Object Identifier

10.1055/s-2005-869542

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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