Topical 0.5% nifedipine vs. lateral internal sphincterotomy for the treatment of chronic anal fissure: long-term follow-up.

Author: AtmatzidisKonstantinos, DimiropoulosStavros, KatsinelosPanagiotis, KoutelidakisIoannis, PapaziogasBasilios, ParoutoglouGeorge, SouparisAnastasios

Paper Details 
Original Abstract of the Article :
BACKGROUND: The aim of this study was to compare the efficacy of the local application of 0.5% nifedipine ointment vs. lateral internal sphincterotomy in the healing of chronic anal fissure. PATIENTS AND METHODS: Sixty-four patients with symptomatic chronic anal fissures were randomly assigned to 0...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1007/s00384-005-0766-x

データ提供:米国国立医学図書館(NLM)

Chronic Anal Fissure: Finding Relief in the Desert of Pain

[Chronic anal fissure] is a painful condition that can significantly impact quality of life. This study compares the effectiveness of [topical 0.5% nifedipine ointment] and [lateral internal sphincterotomy] in treating this condition, offering potential solutions for relief from this uncomfortable problem.

Two Approaches to Healing: Nifedipine vs. Sphincterotomy

The study found that both [topical nifedipine] and [lateral internal sphincterotomy] were effective in healing chronic anal fissures, with similar healing rates. However, [topical nifedipine] was associated with a higher incidence of side effects. This highlights the need for individualized treatment strategies, considering each patient's specific needs and preferences.

A New Frontier in Anal Fissure Treatment: Nifedipine as a Potential Alternative

This research suggests that [topical nifedipine] may represent a promising alternative to [lateral internal sphincterotomy] for treating chronic anal fissures. It highlights the potential of non-surgical approaches to address this condition, offering patients a less invasive option for relief. It's like finding a hidden oasis in the desert of anal fissure pain, offering a new path to healing.

Dr.Camel's Conclusion

Chronic anal fissure can be a difficult journey through a desert of pain. This study offers valuable insights into the potential of topical nifedipine as a new and promising treatment option, providing patients with a potential alternative to surgery. It's a reminder that even in the most sensitive areas, there are often new paths to relief and healing.

Date :
  1. Date Completed 2006-11-28
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

16091912

DOI: Digital Object Identifier

10.1007/s00384-005-0766-x

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.