Chiral cardiovascular drugs: an overview.

Author: RanadeVasant V, SombergJohn C

Paper Details 
Original Abstract of the Article :
Stereochemistry in drug molecules is rapidly becoming an important aspect in drug research, design, and development. Recently, individual stereoisomers of drug molecules with asymmetric centers such as fexofenadine, cetirizine, verapamil, fluoxetine, levalbutarol, and amphetamine, for example, have ...See full text at original site
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引用元:
https://doi.org/10.1097/01.mjt.0000167429.37357.0c

データ提供:米国国立医学図書館(NLM)

Chiral Cardiovascular Drugs: A Tale of Two Isomers

Imagine a camel caravan navigating a complex network of pathways through the desert. This study explores the importance of chirality in cardiovascular drugs, highlighting the distinct properties of different stereoisomers. It's like studying the different types of sand dunes in the desert, understanding the nuances of their structure and impact on the landscape.

This research reviews the importance of chirality in cardiovascular drugs, focusing on the therapeutic activity, side effects, and toxicity of different stereoisomers. It's like carefully analyzing the different paths through a desert, identifying the safest and most efficient routes for a camel caravan. The authors emphasize the need for further research to fully understand the significance of chirality in drug development.

A Twist of Fate: The Importance of Chirality

This study underscores the importance of considering chirality in drug development. It highlights the fact that different stereoisomers of the same drug can have distinct therapeutic effects and side effects. It's like recognizing the different properties of sand, some smooth and easy to navigate, others rough and potentially dangerous for a camel caravan.

Navigating the Desert of Drug Development: A New Perspective

This research offers a new perspective on drug development, emphasizing the importance of considering chirality. It's a reminder that the desert of drug development is complex and multifaceted, requiring careful attention to detail to ensure safe and effective treatments.

Dr. Camel's Conclusion

This study sheds light on the crucial role of chirality in drug development. It's a reminder that even the smallest details can have a significant impact on the effectiveness and safety of medications. It's a journey through the desert of drug development, seeking to navigate its complexities and uncover new solutions for improving patient health.

Date :
  1. Date Completed 2005-12-21
  2. Date Revised 2019-11-09
Further Info :

Pubmed ID

16148430

DOI: Digital Object Identifier

10.1097/01.mjt.0000167429.37357.0c

Related Literature

SNS
PICO Info
in preparation
Languages

English

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