Absorption of topical moxifloxacin ophthalmic solution into human aqueous humor.

Author: DahlinDavid C, FaulknerRobert D, KatzHarold R, LaneStephen S, MasketSamuel, McCueBette A, OrrSusan C, SallKenneth

Paper Details 
Original Abstract of the Article :
PURPOSE: To investigate the absorption of moxifloxacin into human aqueous humor after administration of moxifloxacin hydrochloride ophthalmic solution, 0.5% as base. METHODS: Cataract patients were randomly allocated to receive 1 drop every 15 minutes for 4 doses before surgery (group 1) or 1 drop ...See full text at original site
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引用元:
https://doi.org/10.1097/01.ico.0000157423.78275.a2

データ提供:米国国立医学図書館(NLM)

Moxifloxacin: A Sandstorm of Protection

The field of ophthalmology is constantly seeking new ways to protect our precious eyes from infections. This research dives deep into the desert of the human eye, exploring the effectiveness of moxifloxacin ophthalmic solution in combating bacterial endophthalmitis. This study employed a rigorous methodology, carefully comparing two different dosing regimens of moxifloxacin in patients undergoing cataract surgery. The researchers aimed to understand how this medication penetrates the human aqueous humor, the fluid that nourishes the eye, and ultimately how this affects its ability to prevent infections.

More Moxifloxacin, More Protection?

The findings revealed that both dosing regimens resulted in significant moxifloxacin concentrations in the aqueous humor, far exceeding the minimum inhibitory concentrations (MICs) for common bacterial culprits in endophthalmitis. This suggests that either regimen could effectively protect against post-operative infections, like a sturdy fortress against an encroaching sandstorm.

Keeping Your Eyes Safe in the Desert

While the study provides promising results, it's important to remember that post-operative care is a collaborative effort between patients and their ophthalmologists. Following your doctor's instructions, maintaining good hygiene, and reporting any unusual symptoms is crucial. Think of it as navigating a vast desert – preparation and awareness are essential for a safe and successful journey.

Dr.Camel's Conclusion

This research offers a beacon of hope for preventing bacterial endophthalmitis, a condition that can be quite a sight for sore eyes! The study suggests that both moxifloxacin regimens may provide sufficient protection against infection, but careful monitoring and adherence to post-operative care instructions remain key to ensuring a clear vision of the future.

Date :
  1. Date Completed 2006-02-07
  2. Date Revised 2019-09-17
Further Info :

Pubmed ID

16227840

DOI: Digital Object Identifier

10.1097/01.ico.0000157423.78275.a2

Related Literature

SNS
PICO Info
in preparation
Languages

English

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