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In vitro and in vivo potency of moxifloxacin and moxifloxacin ophthalmic solution 0.5%, a new topical fluoroquinolone.

Author: CuppGale A, DajcsJoseph J, SchlechBarry A, StromanDavid W

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

The fourth-generation fluoroquinolones, such as moxifloxacin and gatifloxacin, have enhanced activity against gram-positive bacteria while retaining potent activity against most gram-negative bacteria.
Paper Details　
Original Abstract of the Article :
Fluoroquinolones are a class of synthetic antibacterial agents that were approved for ocular therapy in 1991 and have become popular therapy for the treatment and prevention of various ocular infections. These agents are synthetic, broad-spectrum, rapidly bactericidal, and have good penetration into...See full text at original site
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引用元：
https://doi.org/10.1016/j.survophthal.2005.06.002

データ提供：米国国立医学図書館（NLM）

Moxifloxacin: A Powerful Weapon Against Ocular Infections

The field of [ocular infections] treatment has seen the emergence of [fluoroquinolones] as a potent class of [antibacterial agents]. This review examines the [in vitro and in vivo potency] of [moxifloxacin] and its [ophthalmic solution], a [fourth-generation fluoroquinolone]. The review highlights the [broad-spectrum bactericidal activity] of [moxifloxacin], its [enhanced activity against gram-positive bacteria], and its [improved penetration into the anterior chamber]. The authors discuss the [in vitro potency] and [in vivo activity] of [moxifloxacin] in treating and preventing [experimental ocular infections], showcasing its potential as a valuable tool in combating [ocular infections].

A New Frontier in Ocular Infection Treatment

This review underscores the importance of [continuous innovation] in the field of [ocular infections] treatment. The development of [moxifloxacin], with its [enhanced efficacy and improved penetration], represents a significant advancement in combating these infections. The research, akin to a desert oasis offering a vital source of water, provides a new path toward more effective treatment options.

Protecting the Eyesight

This review emphasizes the importance of protecting [eye health]. Just as a camel relies on its keen eyesight to navigate the desert, individuals rely on their vision for countless daily tasks. The development of [moxifloxacin] offers a new weapon in the fight against [ocular infections], helping to preserve and protect this precious sense.

Dr. Camel's Conclusion

This review underscores the importance of [antibacterial agents] in combating [ocular infections]. Moxifloxacin emerges as a promising fourth-generation fluoroquinolone, offering enhanced efficacy and improved penetration into the anterior chamber. Like a camel navigating the vast desert, we must continue to seek out innovative solutions to protect our eyesight and maintain optimal vision health.

Date :
  1. Date Completed 2006-01-03
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

16257308

DOI: Digital Object Identifier

10.1016/j.survophthal.2005.06.002

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Article Analysis
・Effects of moxifloxacin ophthalmic
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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