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Safety of moxifloxacin as shown in animal and in vitro studies.

Author: HoltWilliam F, KastnerPhilip R, McGeeDavid H, RiceRebecca L

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Moxifloxacin ophthalmic solution 0.5% provides antibacterial potency and high penetration of target ocular tissues. It is safe and well tolerated in patients with bacterial conjunctivitis.
Paper Details　
Original Abstract of the Article :
Topical treatment of ocular bacterial infection is practiced widely, and the choice of the antibacterial agent depends on the nature of the infection, including the susceptibility of the organism, the tissue affected, and the safety profile of the agent. Moxifloxacin is a fourth-generation fluoroqui...See full text at original site
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引用元：
https://doi.org/10.1016/j.survophthal.2005.05.003

データ提供：米国国立医学図書館（NLM）

Safety of Moxifloxacin as Shown in Animal and In Vitro Studies

Moxifloxacin is a fourth-generation fluoroquinolone antibiotic used for ophthalmic infections. This study investigates the safety profile of moxifloxacin ophthalmic solution 0.5% through in vitro and animal studies. The authors provide a comprehensive assessment of moxifloxacin's safety, including its ocular and systemic effects. They also compare the safety profile of moxifloxacin to other fluoroquinolone antimicrobial agents.

Moxifloxacin's Safety Profile

The study found that moxifloxacin demonstrated a favorable safety profile, with a low risk of recognized quinolone-related toxicity. In vitro and animal studies showed that moxifloxacin's cytotoxicity potential is comparable to other fluoroquinolones. This research provides evidence that moxifloxacin ophthalmic solution 0.5% is a safe and effective treatment option for ocular bacterial infections.

Using Moxifloxacin Safely

Moxifloxacin ophthalmic solution 0.5% is generally well-tolerated, but it is crucial to use it as directed by your healthcare provider. Follow the prescribed dosage and duration of treatment to minimize the risk of potential side effects.

Dr. Camel's Conclusion

This study, like a refreshing oasis in the desert of drug development, provides reassurance about the safety of moxifloxacin ophthalmic solution 0.5%. The research demonstrates that moxifloxacin is a safe and effective treatment option for ocular bacterial infections. It's important to remember that all medications have potential side effects, so consulting with your healthcare provider is crucial before starting any new treatment.

Date :
  1. Date Completed 2006-01-03
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

16257310

DOI: Digital Object Identifier

10.1016/j.survophthal.2005.05.003

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PICO Info
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Languages

English

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