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Lithium intoxication associated with intramuscular ziprasidone in schizoaffective patients.
Author: FrolovaKatherina, HausmannMichael, LernerVladimir, MiodownikChanoch
Original Abstract of the Article :
Antipsychotic agents have been used for the treatment of mood disorders in schizophrenic and schizoaffective patients. It has also been suggested that combinations of lithium and antipsychotics may be more effective than either class alone in treatment of schizoaffective patients. Lithium is known t...See full text at original site
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引用元:
https://doi.org/10.1097/01.wnf.0000194037.75621.78
データ提供:米国国立医学図書館(NLM)
Exploring the Intersection of Lithium and Ziprasidone
The treatment of [schizoaffective disorders] often involves a combination of medications, aiming to achieve optimal symptom control. This case report examines the potential for drug interactions between [lithium] and [ziprasidone], two commonly used medications for [schizoaffective patients]. The authors describe two patients who developed [lithium intoxication] after receiving [intramuscular ziprasidone treatment].
Drug Interactions and Lithium Toxicity
The case report suggests that the rapid increase in [ziprasidone serum level] after [parenteral administration] may have affected [lithium excretion], leading to [lithium intoxication]. This highlights the potential for drug interactions, even when using medications commonly prescribed for the same condition. It's crucial for clinicians to be aware of these potential interactions and carefully monitor patients receiving combination therapy.
Navigating the Complexities of Polypharmacy
This case report serves as a reminder of the complexities of [polypharmacy], where multiple medications are prescribed concurrently. Careful consideration of potential drug interactions is essential to ensure patient safety. Just as a desert traveler needs to be mindful of the potential hazards along their journey, so too must clinicians navigate the intricate web of interactions between different medications.
Dr.Camel's Conclusion
The treatment of schizoaffective disorders, like a desert journey, requires careful planning and attention to detail. This case report underscores the importance of considering potential drug interactions when prescribing multiple medications. It's a reminder that even with the best intentions, unexpected consequences can arise when medications are combined, highlighting the need for vigilance and a thorough understanding of pharmacodynamics.
Date :
- Date Completed 2006-03-02
- Date Revised 2019-09-17
Further Info :
Related Literature
English
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