Metabolic modulators for chronic cardiac ischemia.

Author: AroraRohit, ParangPirouz, SinghBramah

Paper Details 
Original Abstract of the Article :
Many patients with ischemic heart disease continue to experience anginal symptoms despite revascularization and treatment with antianginal medications. The effectiveness of current anti-ischemic medications is limited by their hemodynamic side effects, such as hypotension and bradycardia, which resu...See full text at original site
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引用元:
https://doi.org/10.1177/107424840501000402

データ提供:米国国立医学図書館(NLM)

Metabolic Modulators for Chronic Cardiac Ischemia: A New Paradigm for Treatment

Chronic cardiac ischemia, a condition characterized by insufficient blood flow to the heart, can cause debilitating chest pain and lead to serious complications. While current anti-ischemic medications offer some relief, their efficacy is often limited by side effects such as hypotension and bradycardia. This study explores a new paradigm for treating chronic cardiac ischemia, focusing on metabolic modulators that enhance the efficiency of the heart muscle rather than simply reducing its workload. The authors review five novel agents under investigation: ranolazine, trimetazidine, L-carnitine, ribose, and dichloroacetate. They highlight the potential of these agents to improve myocardial efficiency, potentially offering a safer and more effective treatment option for chronic cardiac ischemia.

Metabolic Modulators: A Promising Avenue for Heart Health

This research sheds light on a new approach to treating chronic cardiac ischemia, focusing on metabolic modulators that enhance myocardial efficiency. The study's review of five novel agents offers promising avenues for exploring safer and more effective treatment options for this challenging condition. Further research is crucial to evaluate the efficacy and safety of these agents, potentially leading to significant improvements in patient care.

Understanding Chronic Cardiac Ischemia: Seeking Effective Treatment

For individuals facing chronic cardiac ischemia, seeking effective treatment options is paramount. This study provides a valuable overview of emerging therapies, focusing on metabolic modulators that enhance myocardial efficiency. It's essential to discuss with your doctor the potential benefits and risks of different treatment options, ensuring that the chosen approach effectively manages your condition and improves your quality of life.

Dr. Camel's Conclusion

Like a camel navigating a desert with limited water sources, those with chronic cardiac ischemia face a challenging condition with limited treatment options. This study, like a wellspring of knowledge, unveils a new paradigm for treatment, focusing on metabolic modulators that enhance myocardial efficiency. It's a reminder that ongoing research and innovation continue to offer hope for better treatments and healthier lives.

Date :
  1. Date Completed 2006-04-21
  2. Date Revised 2017-02-14
Further Info :

Pubmed ID

16382258

DOI: Digital Object Identifier

10.1177/107424840501000402

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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