Effect of buprenorphine and antiretroviral agents on the QT interval in opioid-dependent patients.

Author: BakerJennifer R, BestAl M, McCance-KatzElinore F, PadePatricia A

Paper Details 
Original Abstract of the Article :
Cardiac arrhythmias have been linked to treatment with methadone and levacetylmethadol. HIV-positive patients often have conditions that place them at risk for QT interval prolongation including HIV-associated dilated cardiomyopathy, coronary artery disease as a consequence of highly active antiretr...See full text at original site
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引用元:
https://doi.org/10.1345/aph.1G524

データ提供:米国国立医学図書館(NLM)

Effect of Buprenorphine and Antiretroviral Agents on the QT Interval

The treatment of opioid dependence and HIV infection, much like navigating a treacherous desert landscape, requires careful consideration of potential side effects. This study, akin to a team of researchers mapping the terrain of cardiac risks associated with these treatments, investigates the effects of buprenorphine and antiretroviral agents on the QT interval.

Navigating the Desert of Cardiac Risks

This study, like a compass guiding a traveler through a potentially dangerous desert, assesses the cardiac risks associated with buprenorphine and antiretroviral agents. The researchers find that buprenorphine, unlike other opioid treatments, has not been linked to QT interval prolongation. This finding provides valuable insights into the potential cardiac safety of buprenorphine, offering a safer option for patients with existing cardiac conditions.

Protecting the Heart in the Desert

This study, like a protective barrier around a fragile oasis, emphasizes the importance of minimizing cardiac risks in patients receiving treatment for opioid dependence and HIV infection. The researchers' findings highlight the need for careful monitoring and consideration of alternative treatments when appropriate, ensuring the safety and well-being of patients navigating the challenging terrain of these conditions.

Dr.Camel's Conclusion

This study serves as a valuable reminder that the journey through the desert of chronic conditions can be fraught with potential risks. The researchers provide important insights into the cardiac safety of buprenorphine, offering a safer option for patients with existing cardiac conditions. By understanding these potential risks and implementing appropriate precautions, we can protect the hearts of patients and ensure a smoother and safer journey through the desert of treatment.
Date :
  1. Date Completed 2006-04-26
  2. Date Revised 2018-12-11
Further Info :

Pubmed ID

16507617

DOI: Digital Object Identifier

10.1345/aph.1G524

Related Literature

SNS
PICO Info
in preparation
Languages

English

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