[Erythema annulare centrifugum Darier. Successful therapy with topical calcitriol and 311 nm-ultraviolet B narrow band phototherapy].

Author: Braun-FalcoM, Bruckner-TudermanL, ReuterJ, TermeerC

Paper Details 
Original Abstract of the Article :
Erythema annulare centrifugum is an acute dermatosis of unclear etiology, which presents with annular erythematous lesions with marginal scale. Therapeutically, systemic and topical glucocorticosteroids are used primarily. We treated a patient with large lesions in the area of the thighs resistant t...See full text at original site
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引用元:
https://doi.org/10.1007/s00105-006-1131-x

データ提供:米国国立医学図書館(NLM)

Erythema Annulare Centrifugum: A Desert Oasis of Treatment Options

This research dives into the world of dermatology, specifically focusing on a skin condition called Erythema Annulare Centrifugum. It's a bit like a mystery in the desert - we're not entirely sure what causes it, but we know it manifests as a circular rash with a scaly border. Typically, the go-to treatment is like a soothing balm in the desert heat - corticosteroids, either applied directly to the skin or taken orally. However, this study takes a different approach, exploring the effectiveness of a combination therapy - topical calcitriol (a vitamin D3 analogue) and 311 nm narrowband ultraviolet B phototherapy.

A New Oasis: Effective Combination Therapy

The researchers found that this combination therapy was successful in treating a patient with large lesions on their thighs, a condition that didn't respond well to conventional corticosteroid treatment. This finding is like discovering a new oasis in the vast desert - a promising alternative treatment option. After four weeks of treatment, the patient's skin lesions were nearly completely cleared, and there were no side effects. This suggests that the combination of calcitriol and narrowband UVB phototherapy could be a valuable tool for managing Erythema Annulare Centrifugum, potentially offering a more targeted and gentle approach compared to corticosteroids.

Navigating the Desert of Skin Conditions

This study highlights the importance of exploring alternative treatment options for skin conditions. While corticosteroids have been the traditional remedy, this research suggests that combination therapy might offer a more effective and well-tolerated approach. As a desert explorer always seeking a new oasis, I'm excited about the potential of this combination therapy to provide relief for individuals with Erythema Annulare Centrifugum. It's a reminder that there's always more to discover in the ever-expanding desert of medical knowledge.

Dr. Camel's Conclusion

This research presents a promising alternative treatment for Erythema Annulare Centrifugum. The combination of topical calcitriol and 311 nm narrowband UVB phototherapy effectively cleared the lesions in a patient resistant to conventional corticosteroid treatment. While further research is needed to confirm these findings and explore the long-term efficacy, this discovery is a significant step towards providing more targeted and effective treatment options for skin conditions.
Date :
  1. Date Completed 2007-08-17
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

16636867

DOI: Digital Object Identifier

10.1007/s00105-006-1131-x

Related Literature

SNS
PICO Info
in preparation
Languages

German

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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