CYP2D6 genotype and venlafaxine-XR concentrations in depressed elderly.

Author: BegleyAmy E, KirshneMargaret A, MulsantBenoit H, PollockBruce G, ReynoldsCharles F, RomkesMarjorie, WhyteEllen M

Paper Details 
Original Abstract of the Article :
The elderly are at increased risk for medication-related adverse events. Recent reports indicate that venlafaxine may put the elderly at increased risk of cardio- and cerebrovascular adverse events. We investigated the relationship between the CYP2D6 polymorphism and steady-state plasma concentratio...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1002/gps.1522

データ提供:米国国立医学図書館(NLM)

Venlafaxine and the Elderly: Navigating the Sands of Pharmacology

The field of [pharmacology] is a vast desert, filled with a complex interplay of drugs, dosage, and individual responses. This study, like a seasoned desert guide, examines the interaction between [venlafaxine] and the elderly population, highlighting potential risks and individual variations. The research explores the relationship between the [CYP2D6 polymorphism] and the effectiveness of [venlafaxine] in elderly individuals, seeking to understand the factors that influence drug response.

Individual Variations in Drug Response

The study's findings underscore the importance of recognizing individual variations in drug response. Like different oases in the desert, individuals may react differently to the same medication due to genetic and other factors. This research highlights the need for careful monitoring and personalized approaches to medication management, especially for vulnerable populations like the elderly.

Safety First: Navigating the Desert of Medications

This study serves as a reminder of the importance of understanding the potential risks and benefits of medications, particularly for the elderly. Like a wise camel choosing its path through the desert, it's essential to make informed decisions about medication use, taking into account individual factors and potential side effects.

Dr.Camel's Conclusion

The research underscores the importance of personalized medicine and the need to tailor treatment plans to the individual patient. It also highlights the critical role of careful monitoring and ongoing assessment to ensure medication safety and effectiveness. By embracing these principles, we can navigate the complexities of pharmacology and improve patient outcomes.

Date :
  1. Date Completed 2007-02-16
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

16642541

DOI: Digital Object Identifier

10.1002/gps.1522

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.