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Side effects of sirolimus.

Author: HallerH, MengelM, MerkelS, MogilevskajaN, SchwarzA

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Sirolimus, an mTOR inhibitor, improves renal transplant function but may be associated with adverse events including hyperlipidemia, anemia, and proteinuria. Careful monitoring is required, especially in patients with preexisting glomerular disease.
Paper Details　
Original Abstract of the Article :
The mTOR inhibitor sirolimus improves renal transplant function compared with the nephrotoxic calcineurin inhibitors. We evaluated retrospectively the adverse events in 119 of 134 patients getting sirolimus which seemed to be caused by sirolimus. Patients were converted to sirolimus because of malig...See full text at original site
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引用元：
https://doi.org/10.1016/j.transproceed.2006.01.044

データ提供：米国国立医学図書館（NLM）

Sirolimus: A Double-Edged Sword in the Desert of Organ Transplantation

This research examines the use of sirolimus, an immunosuppressant drug, in kidney transplantation. They review the potential benefits and risks of using sirolimus, highlighting its ability to improve transplant function while also presenting a risk of side effects, such as increased proteinuria and glomerulopathy. This study emphasizes the importance of careful monitoring and individualized treatment decisions when using sirolimus in kidney transplantation.

Sirolimus: A Balancing Act in Transplantation

This research highlights the complexities of using sirolimus in kidney transplantation. It's like navigating a desert with a double-edged sword – sirolimus can offer protection but also carries potential risks. This study emphasizes the need for careful monitoring and personalized treatment approaches to maximize the benefits and minimize the risks of this medication.

Living Well With Organ Transplantation

This research underscores the importance of open communication with your doctor about any concerns or side effects you experience after organ transplantation. It's a reminder that organ transplantation is a complex process, and that careful monitoring and ongoing management are crucial for ensuring a successful outcome.

Dr.Camel's Conclusion

This research explores the complexities of using sirolimus in kidney transplantation, highlighting both its potential benefits and risks. It's a reminder that even in the seemingly arid landscape of organ transplantation, where every step is critical, there are always unexpected challenges and opportunities for innovation.

Date :
  1. Date Completed 2006-08-11
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

16647452

DOI: Digital Object Identifier

10.1016/j.transproceed.2006.01.044

Related Literature

Article Analysis
・Side Effects of sirolimus
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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