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Calcium acetate used as phosphate binding treatment in uremic hyperphosphatemia.
Author: DanielsonB G, FellströmB, WikströmB
Original Abstract of the Article :
Due to toxic side effects of aluminum-containing agents for treatment of uremic hypophosphatemia, much interest has been focused upon aluminum-free phosphate binder alternatives. From results of experimental studies with calcium acetate, this salt has been suggested as a possible effective and safe ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/1680430
データ提供:米国国立医学図書館(NLM)
Calcium Acetate: A Phosphate Binder in Uremia
This study investigates the effectiveness and safety of calcium acetate as a phosphate binder in patients with uremic hyperphosphatemia. The researchers conducted a [clinical trial of 30 uremic patients] who were previously treated with aluminum and/or calcium carbonate. They evaluated the effectiveness of calcium acetate in controlling serum phosphate levels and monitored for potential side effects.
Calcium Acetate Demonstrates Effectiveness and Safety in Uremia
The study found that calcium acetate effectively controlled serum phosphate levels without significantly impacting serum calcium, alkaline phosphatase, or parathyroid hormone levels. The researchers observed a significant decrease in serum aluminum levels during the study. While moderate hypercalcemia was observed in a small number of patients, calcium acetate appeared to be a safe and effective alternative to aluminum-containing phosphate binders.
Managing Uremia: A Balancing Act
This study emphasizes the importance of [managing hyperphosphatemia] in patients with uremia, while minimizing the risk of aluminum toxicity. The researchers highlight the potential of calcium acetate as a [safe and effective phosphate binder], offering a valuable alternative for managing this challenging condition. The findings encourage further research into the long-term effects of calcium acetate and its role in improving overall outcomes for patients with uremia.
Dr.Camel's Conclusion
Imagine a camel caravan navigating a desert landscape, searching for precious resources like water. This study is like a discovery of a new oasis, a source of calcium acetate, which proves to be a safe and effective way to manage hyperphosphatemia in patients with uremia. This research offers a beacon of hope for these individuals, potentially improving their quality of life and easing the burden of this complex condition.
Date :
- Date Completed 1991-11-21
- Date Revised 2013-11-21
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English
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