Paper Details 
Original Abstract of the Article :
Relieving the symptoms of angina and improving the quality of life and functional status are important objectives in the management of patients with chronic stable angina. A high heart rate induces or exacerbates myocardial ischemia and angina because it both increases oxygen demand and decreases my...See full text at original site
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引用元:
https://doi.org/10.1159/000095429

データ提供:米国国立医学図書館(NLM)

Heart Rate: A Key Target for Angina Relief

Angina, a condition where the heart doesn't get enough oxygen, is like a stubborn camel refusing to move forward. This research embarks on a journey to understand the role of heart rate in managing angina and explores alternative strategies to reduce its symptoms.

The researchers discovered that a high heart rate can exacerbate angina by increasing oxygen demand and reducing blood flow to the heart. While beta-blockers are often used to lower heart rate and alleviate symptoms, they can have side effects, like fatigue, depression, and sexual dysfunction. Therefore, they sought to explore other avenues for heart rate reduction.

They found that calcium antagonists, like verapamil and diltiazem, and a new drug called ivabradine, can also effectively slow heart rate. Ivabradine, acting like a skilled camel jockey, selectively slows the heart rate without interfering with the heart's pumping function. Clinical trials have shown that ivabradine effectively reduces angina attacks and improves heart function.

A Promising New Approach to Angina Treatment

Ivabradine stands out as a promising alternative for patients who cannot tolerate beta-blockers or need additional heart rate reduction. The study's findings suggest that ivabradine may provide a more tailored and effective treatment for angina, offering a smoother ride for patients.

Health Impacts and Lifestyle Tips

If you have angina, talk to your doctor about the best treatment options for you. They can help you find the best approach to manage your symptoms and improve your quality of life. Lifestyle modifications, like regular exercise and a healthy diet, can also be beneficial in managing angina.

Dr.Camel's Conclusion

This research is like a camel caravan finding a new oasis in the desert of angina treatment. Ivabradine offers a novel and effective way to manage angina symptoms, potentially improving the lives of many patients. This journey through the desert of heart health continues, but with promising new approaches like ivabradine, we can hope for a brighter future.

Date :
  1. Date Completed 2006-11-22
  2. Date Revised 2019-07-10
Further Info :

Pubmed ID

16936473

DOI: Digital Object Identifier

10.1159/000095429

Related Literature

SNS
PICO Info
in preparation
Languages

English

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