Comparison of felodipine and hydrochlorothiazide for the treatment of mild to moderate hypertension in black Africans.

Author: LearyW P, MaharajB

Paper Details 
Original Abstract of the Article :
A double-blind, parallel-group study was performed to assess the antihypertensive effects and tolerability of felodipine and hydrochlorothiazide (HCT) in black patients with mild to moderate uncomplicated hypertension [entry supine diastolic blood pressure (DBP) of 96-116 mm Hg]. The medicines were ...See full text at original site
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引用元:
https://doi.org/10.1097/00005344-199015004-00028

データ提供:米国国立医学図書館(NLM)

Comparing Medications for Hypertension in Black Africans

High blood pressure, or hypertension, is a common concern, particularly in certain populations. This study focused on Black Africans with mild to moderate hypertension, comparing the effectiveness and tolerability of two commonly used medications: felodipine and hydrochlorothiazide (HCT). The researchers embarked on a double-blind, parallel-group study, meaning neither the patients nor the researchers knew which medication each patient received. This approach is like conducting a carefully controlled experiment in a vast desert of hypertension research, ensuring unbiased results.

Felodipine Emerges as a More Effective Treatment

The results showed that felodipine was more effective in reducing both systolic and diastolic blood pressure compared to HCT. This finding suggests that felodipine might be a better choice for certain Black African patients with hypertension. The study also found that felodipine was associated with fewer side effects than HCT. Think of it like choosing the smoothest path through a sandy desert, avoiding the bumpy and potentially hazardous terrain.

Navigating Hypertension Treatment

This research underscores the need for personalized treatment approaches to hypertension. While felodipine showed greater efficacy in this study, it's important to remember that each individual's response to medication can vary. It's always crucial to consult a doctor to determine the best treatment plan for your unique needs. Navigating the desert of hypertension requires a knowledgeable guide, and your doctor is your best resource.

Dr. Camel's Conclusion

This study reminds us that the landscape of hypertension treatment can be complex, like a vast and diverse desert. It highlights the importance of personalized care and considering factors like race and ethnicity when choosing the most appropriate medication. Remember, consulting your doctor is like having a trusty camel guide to help you navigate the path to better health.

Date :
  1. Date Completed 1990-07-17
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

1693738

DOI: Digital Object Identifier

10.1097/00005344-199015004-00028

Related Literature

SNS
PICO Info
in preparation
Languages

English

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