Pulse itraconazole vs. continuous terbinafine for the treatment of dermatophyte toenail onychomycosis in patients with diabetes mellitus.

Author: GoverM D, GuptaA K, LyndeC W

Paper Details 
Original Abstract of the Article :
Oral terbinafine and oral itraconazole are two of the most common agents used for the treatment of toenail dermatophyte onychomycosis. Despite the fact that diabetic patients are more likely to have onychomycosis than normal individuals are, there is little research into the efficacy of standard ora...See full text at original site
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引用元:
https://doi.org/10.1111/j.1468-3083.2006.01698.x

データ提供:米国国立医学図書館(NLM)

Toenail Fungus: A Stubborn Desert Beast

Toenail onychomycosis, a fungal infection that affects the toenails, can be a persistent and bothersome ailment. It's like a stubborn desert beast, refusing to leave without a fight. This study examines two common antifungal medications, oral terbinafine and oral itraconazole, for their effectiveness in treating toenail onychomycosis in patients with diabetes mellitus.

While both drugs are effective, this study aimed to determine the most effective treatment option, particularly in a population with diabetes, who are more susceptible to toenail fungus infections. The researchers compared the effectiveness of pulse itraconazole (given in cycles) with continuous terbinafine, both common treatment regimens for toenail onychomycosis.

Finding the Right Weapon: Pulse or Continuous Therapy?

The study suggests that both pulse itraconazole and continuous terbinafine can be effective in treating toenail onychomycosis in diabetic patients. However, this study lacked sufficient data to determine which treatment was more effective in this population. Further research is necessary to guide clinical practice and determine the most effective and safe treatment option for diabetic patients with toenail fungus infections.

Fighting the Desert Beast: A Multi-Pronged Approach

To combat toenail onychomycosis effectively, a multi-pronged approach is often necessary. This includes proper hygiene, maintaining healthy blood sugar levels, and following your doctor's recommendations for medication. It is essential to consult with a healthcare professional to find the best treatment option that aligns with your individual needs.

Dr.Camel's Conclusion

Like a camel navigating a treacherous desert, the fight against toenail fungus requires persistence and careful consideration. This study provides insights into potential treatment options, but further exploration is needed to pinpoint the most effective strategy for diabetic patients facing this stubborn desert beast.

Date :
  1. Date Completed 2007-01-25
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

17062029

DOI: Digital Object Identifier

10.1111/j.1468-3083.2006.01698.x

Related Literature

SNS
PICO Info
in preparation
Languages

English

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