Anagrelide, a therapy for thrombocythemic states: experience in 577 patients. Anagrelide Study Group.

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Paper Details 
Original Abstract of the Article :
PURPOSE: To evaluate the safety and efficacy of anagrelide when used to reduce platelet counts in patients with thrombocytosis. PATIENTS AND METHODS: Five hundred seventy-seven patients were treated with anagrelide to control the thrombocytosis of chronic myeloproliferative diseases. Three hundred ...See full text at original site
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引用元:
https://doi.org/10.1016/0002-9343(92)90017-6

データ提供:米国国立医学図書館(NLM)

Anagrelide: A New Weapon in the Fight Against Thrombocytosis

Thrombocytosis, a condition characterized by an elevated platelet count, can lead to serious complications, including blood clots. This research examines the safety and efficacy of anagrelide, a medication used to reduce platelet counts in patients with thrombocytosis. The study, conducted on a large cohort of patients with various types of thrombocytosis, evaluated the effectiveness of anagrelide in controlling platelet counts and assessed its safety profile.

Anagrelide: A Promising Treatment for Thrombocytosis

The study's findings demonstrate the effectiveness of anagrelide in controlling platelet counts in patients with thrombocytosis. Anagrelide, administered in a dose of 0.5 mg to 1.0 mg four times daily, effectively reduced platelet counts by 50% or to less than 600,000/mm3 in a significant number of patients. The study also revealed that anagrelide was generally well-tolerated, with the most common side effects being neurological, gastrointestinal, and cardiac.

Anagrelide: A New Hope for Thrombocytosis Patients

This research provides valuable insights into the effectiveness and safety of anagrelide for treating thrombocytosis. The study's findings suggest that anagrelide could offer a viable treatment option for patients with thrombocytosis, particularly those who have not responded to other therapies. This research underscores the importance of exploring new and effective treatment options for this condition and improving the lives of patients affected by it.

Dr.Camel's Conclusion

The study's findings highlight the potential of anagrelide as a safe and effective treatment for thrombocytosis. The research suggests that anagrelide could provide a valuable therapeutic option for patients struggling with this condition, potentially leading to improved outcomes and a better quality of life.

Date :
  1. Date Completed 1992-02-18
  2. Date Revised 2019-06-26
Further Info :

Pubmed ID

1731512

DOI: Digital Object Identifier

10.1016/0002-9343(92)90017-6

Related Literature

SNS
PICO Info
in preparation
Languages

English

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