Treatment of pruritus with topically applied opiate receptor antagonist.

Author: BigliardiPaul L, Bigliardi-QiMei, BüchnerStanislaw, JostGerhard, RufliTheo, StammerHolger

Paper Details 
Original Abstract of the Article :
BACKGROUND: Pruritus is the most common and distressing skin symptom, and treatment of itch is a problem for thousands of people. The currently available therapies are not very effective. Therefore there is an urgent need to find new effective topical drugs against itching. OBJECTIVE: We conducted ...See full text at original site
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引用元:
https://doi.org/10.1016/j.jaad.2007.01.007

データ提供:米国国立医学図書館(NLM)

Topical Naltrexone for Pruritus: A Novel Approach to Itch Relief

Pruritus, or itching, is a common and often distressing symptom that can significantly impact quality of life. This research explores the potential therapeutic benefits of topical naltrexone, an opioid receptor antagonist, in treating severe pruritus. The study presents findings from two separate studies, including an open pilot study and a double-blind, placebo-controlled, crossover trial. The research highlights the promising efficacy of topical naltrexone in reducing itch symptoms in patients with various pruritic skin disorders, offering a novel approach to managing this challenging condition.

Topical Naltrexone: A Potential Breakthrough for Pruritus Management

This research presents compelling evidence for the potential of topical naltrexone as a novel and effective treatment for pruritus. The findings from both the open pilot study and the placebo-controlled trial suggest that topical naltrexone can significantly reduce itch symptoms in patients with various pruritic skin disorders. These findings offer hope for a more effective and targeted approach to managing pruritus, potentially improving the quality of life for individuals struggling with this common and often debilitating symptom.

Pruritus: Navigating the Desert of Itch

This research underscores the importance of finding effective treatments for pruritus, a condition that can significantly impact quality of life. The study explores the potential benefits of topical naltrexone, an opioid receptor antagonist, as a novel approach to managing itch symptoms. Remember, the desert of itching can be vast and unforgiving, but by exploring new avenues for treatment, we can find oases of relief and improve the well-being of those struggling with this challenging condition. This research offers hope for a brighter future for those seeking relief from the relentless torment of pruritus.

Dr. Camel's Conclusion

This research offers a beacon of hope for those struggling with the relentless itch of pruritus. Imagine pruritus as a persistent desert wind, constantly irritating and disrupting your peace. Topical naltrexone acts as a refreshing oasis, providing relief from the relentless itch and restoring a sense of comfort. While more research is needed to fully explore the potential of this novel approach, the findings offer a promising path forward in the quest to manage pruritus effectively. Remember, even in the harshest deserts, there is always hope for finding oases of relief and improving the quality of life.

Date :
  1. Date Completed 2007-06-07
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

17320241

DOI: Digital Object Identifier

10.1016/j.jaad.2007.01.007

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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