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Preimplantation genetic screening as an alternative to prenatal testing for Down syndrome: preferences of women undergoing in vitro fertilization/intracytoplasmic sperm injection treatment.

Author: BossuytPatrick M M, HaadsmaMaaike L, HeinemanMaas-Jan, KorevaarJohanna C, MastenbroekSebastiaan, ReppingSjoerd, TwiskMoniek, van der VeenFulco

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

The majority of subfertile women surveyed favored preimplantation genetic screening (PGS) for Down syndrome screening, even if it was not 100% sensitive. This study, involving 244 women, found that the acceptability of PGS depended on its potential impact on pregnancy chances and, to a lesser extent, its sensitivity in detecting Down syndrome embryos.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: Although the primary goal of preimplantation genetic screening (PGS) is to increase pregnancy rates in women undergoing IVF/intracytoplasmic sperm injection treatment, it has been suggested that it may also be used as an alternative to prenatal testing for Down syndrome. DESIGN: Trade-of...See full text at original site
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引用元：
https://doi.org/10.1016/j.fertnstert.2006.12.033

データ提供：米国国立医学図書館（NLM）

Preimplantation Genetic Screening (PGS): A New Oasis for Families Seeking to Avoid Down Syndrome

The journey to parenthood can be filled with hope and uncertainty. This study explores the use of preimplantation genetic screening (PGS), a technique that allows for the genetic testing of embryos before implantation, as a way to prevent Down syndrome. The study investigates the preferences of women undergoing in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) regarding the use of PGS as an alternative to prenatal testing for Down syndrome.

Navigating the Sands of Choice: Weighing the Benefits and Risks

This study reveals that most women undergoing IVF/ICSI are open to using PGS for Down syndrome screening, even if it is not 100% effective. The study found that women's willingness to use PGS depends on the potential impact on pregnancy chances and the sensitivity of the test. This decision-making process feels a lot like a caravan choosing the safest path through the desert, weighing the risks and potential rewards.

Empowering Families: Making Informed Choices About PGS

This study provides valuable information for couples considering PGS. It underscores the importance of providing clear and concise information about the procedure's benefits, risks, and limitations. This includes discussing the potential impact on pregnancy chances, the accuracy of the test, and the implications for subsequent prenatal testing. By empowering families with the knowledge they need, we can ensure they make informed decisions that align with their values and goals.

Dr. Camel's Conclusion

This study provides a glimpse into the complex world of reproductive technologies. It highlights the growing use of PGS as a tool for reducing the risk of Down syndrome. As we continue to navigate the ever-evolving landscape of reproductive medicine, it is essential to ensure that families have access to accurate and comprehensive information to make informed decisions that best suit their individual needs and goals.

Date :
  1. Date Completed 2007-11-08
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

17349641

DOI: Digital Object Identifier

10.1016/j.fertnstert.2006.12.033

Related Literature

Article Analysis
・Effective treatment of prenatal testing
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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