Effect of lactulose on calcium and magnesium absorption: a study using stable isotopes in adult men.

Author: AsanoYuzo, HamanoHirokazu, IiyamaYuriko, KokuboSadayuki, KudouHideki, SekiNobuo, TamuraYoshitaka, UenishiKazuhiro, YamauchiKoji

Paper Details 
Original Abstract of the Article :
To evaluate the effect of lactulose on calcium (Ca) and magnesium (Mg) absorption, we performed a clinical trial with a double-blind, randomized, crossover design in 24 healthy adult male volunteers. The absorptions of Ca and Mg were evaluated by a single-labeling method using stable isotopes. The t...See full text at original site
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引用元:
https://doi.org/10.3177/jnsv.53.5

データ提供:米国国立医学図書館(NLM)

The Impact of Lactulose on Calcium and Magnesium Absorption

This research delves into the realm of nutrition and metabolism, focusing on the crucial role of calcium and magnesium in our bodies. It investigates how lactulose, a synthetic sugar commonly used as a laxative, affects the absorption of these vital minerals. The study employed a double-blind, randomized, crossover design in 24 healthy adult men. The authors utilized a single-labeling method with stable isotopes to precisely measure calcium and magnesium absorption after administering varying doses of lactulose alongside a controlled amount of the minerals. They discovered a fascinating trend - higher lactulose dosages corresponded to increased calcium and magnesium absorption, highlighting the potential benefits of lactulose for enhancing mineral bioavailability. This intriguing finding might pave the way for novel approaches to improve mineral absorption, particularly in individuals with dietary deficiencies or compromised gut health.

Lactulose: A Potential Boon for Mineral Absorption

The study concluded that lactulose significantly enhanced the absorption of both calcium and magnesium in adult men. Specifically, the high-dose lactulose group displayed a significant increase in calcium absorption compared to the placebo group, while even the low-dose lactulose group exhibited significantly improved magnesium absorption. These findings are significant as they suggest that lactulose could potentially be used to improve mineral absorption in individuals who are not adequately absorbing these minerals through their diet.

The Impact on Gut Health and Bone Strength

This research sheds light on the fascinating interplay between lactulose, calcium, and magnesium. By enhancing the absorption of these vital minerals, lactulose could potentially contribute to improved bone health and overall well-being. Furthermore, lactulose's known ability to regulate bowel movements could synergize with its mineral-boosting properties to promote better gut health. This research adds another layer to our understanding of lactulose's potential benefits, highlighting its ability to not only alleviate constipation but also play a role in maintaining overall health and well-being.

Dr. Camel's Conclusion

As a seasoned researcher, I find this study particularly exciting, as it opens up a new avenue for exploring the potential benefits of lactulose beyond its traditional role as a laxative. This research suggests that lactulose could play a significant role in improving mineral absorption, potentially impacting bone health, and perhaps even gut health. While more research is necessary to fully explore these possibilities, this study provides a compelling foundation for future investigations. This research could be the key to unlocking a new chapter in our understanding of lactulose's potential role in maintaining overall health.

Date :
  1. Date Completed 2007-12-03
  2. Date Revised 2022-03-10
Further Info :

Pubmed ID

17484373

DOI: Digital Object Identifier

10.3177/jnsv.53.5

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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