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Oxycodone: a pharmacological and clinical review.

Author: Espinosa ArranzE, González BarónM, Ordóñez GallegoA

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study provides a comprehensive overview of oxycodone, a semi-synthetic opioid with agonist activity on mu, kappa, and delta receptors. It discusses the drug's pharmacokinetic properties, mechanism of action, clinical efficacy, side effects, and dosing recommendations. Oxycodone is effective in treating cancer pain and may be associated with less toxicity than morphine in the long term.
Paper Details　
Original Abstract of the Article :
Oxycodone is a semi-synthetic opioid with an agonist activity on mu, kappa and delta receptors. Equivalence with regard to morphine is 1:2. Its effect commences one hour after administration and lasts for 12 h in the controlled-release formulation. Plasma halflife is 3-5 h (half that of morphine) an...See full text at original site
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引用元：
https://doi.org/10.1007/s12094-007-0057-9

データ提供：米国国立医学図書館（NLM）

Oxycodone: A Powerful Pain Reliever

Oxycodone, a semi-synthetic opioid, is widely used for managing pain. This review examines the pharmacological and clinical aspects of oxycodone, exploring its mechanism of action, efficacy, and potential side effects. The authors discuss the use of oxycodone in the management of cancer pain and compare its properties to morphine, another commonly used opioid.

Understanding Oxycodone: A Journey Through the Opioid Landscape

The review provides a comprehensive overview of oxycodone's pharmacological properties, including its affinity for opioid receptors and its metabolic pathways. It highlights the clinical efficacy of oxycodone in managing pain, particularly cancer pain, and discusses its potential side effects, including nausea, constipation, and drowsiness.

Navigating the Risks: A Balanced Approach to Opioid Use

The study underscores the importance of responsible and informed opioid use. Just as a camel must carefully navigate the desert to avoid potential dangers, so too must we approach opioid therapy with caution, considering both the benefits and risks. Working closely with healthcare professionals to manage pain effectively and safely is crucial for maintaining well-being.

Dr. Camel's Conclusion

The review on oxycodone provides valuable insights into the use of this potent pain reliever. Just as we must understand the intricate network of dunes and oases in the desert, so too must we navigate the complex world of opioid therapy with knowledge and understanding.

Date :
  1. Date Completed 2007-10-03
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

17525040

DOI: Digital Object Identifier

10.1007/s12094-007-0057-9

Related Literature

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・Side Effects of oxymorphone
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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