Premedication with montelukast reduces local reactions of allergen immunotherapy.

Author: GamperSimon, HeinzeGeorg, HemmerWolfgang, KinaciyanTamar, StinglGeorg, WöhrlStefan

Paper Details 
Original Abstract of the Article :
Local reactions (LRs) are a very frequent side effect of specific immunotherapy with allergens and can impair patients' adherence. Antihistamine pretreatment--originally introduced as a safety measure to reduce anaphylactic side effects--has been the only treatment option for LRs so far, although th...See full text at original site
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引用元:
https://doi.org/10.1159/000103225

データ提供:米国国立医学図書館(NLM)

Montelukast: A New Weapon Against Allergy Immunotherapy Reactions

Allergy immunotherapy, like a journey through a pollen-filled desert, can sometimes be accompanied by unpleasant side effects. Local reactions (LRs) are a common concern for patients undergoing this treatment, and current strategies for preventing them often fall short. This study investigates the potential of montelukast, a leukotriene antagonist, for reducing the severity of LRs associated with allergen immunotherapy.

Montelukast: A Promising Alternative

The authors compared pretreatment with montelukast to pretreatment with the antihistamine desloratadine and found that montelukast was more effective in reducing LRs. This suggests that montelukast, by targeting the leukotriene pathway, may offer a more effective approach to preventing these reactions.

Navigating Allergy Immunotherapy

This study opens up new possibilities for improving the comfort and tolerability of allergy immunotherapy. By utilizing montelukast, patients can potentially navigate their journey through allergen sensitization with fewer and less severe local reactions. This could ultimately lead to better adherence and more successful treatment outcomes.

Dr.Camel's Conclusion

This research is like a welcome breeze in the desert, offering a new and potentially more effective way to manage the challenges of allergy immunotherapy. Montelukast, with its ability to mitigate LRs, promises a smoother and more comfortable journey for patients seeking relief from their allergies.

Date :
  1. Date Completed 2007-11-13
  2. Date Revised 2021-12-03
Further Info :

Pubmed ID

17536222

DOI: Digital Object Identifier

10.1159/000103225

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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