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Overactive bladder treatments in early phase clinical trials.

Author: ColliEnrico, DigesuGiuseppe Alessandro, OlivieriLorenza

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This article reviews drugs in investigational preclinical and early stage clinical trials for the treatment of overactive bladder (OAB), a highly prevalent condition affecting 17% of the general population. While antimuscarinic drugs are currently the most commonly used treatment, their efficacy is limited by side effects.
Paper Details　
Original Abstract of the Article :
'Overactive bladder' (OAB) is a syndrome that is characterised by symptoms of urgency, with or without urge urinary incontinence, usually with frequency and nocturia [1] . It is a highly prevalent condition affecting 17% of the general population, with a significant negative effect on quality of lif...See full text at original site
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引用元：
https://doi.org/10.1517/13543784.16.7.999

データ提供：米国国立医学図書館（NLM）

The Quest for New Treatments for Overactive Bladder

Overactive bladder (OAB) is a common and often distressing condition that affects millions of people worldwide. This study explores the current landscape of OAB treatments in early-phase clinical trials, focusing on novel approaches beyond traditional antimuscarinic drugs. The study highlights the need for more effective and well-tolerated treatments for OAB, considering the limitations of existing therapies, particularly the high incidence of side effects. It's like searching for a new oasis in the desert of OAB research, seeking out alternative paths to relief.

A New Frontier in OAB Treatment

This study presents a compelling overview of promising new treatment options for OAB. The researchers emphasize the importance of exploring different molecular targets and mechanisms of action beyond traditional antimuscarinics. This research signifies a shift towards personalized approaches to OAB treatment, taking into account individual needs and responses.

Hope for Improved OAB Management

This research offers hope for a future where OAB can be managed more effectively and with fewer side effects. The exploration of new drugs with novel mechanisms of action is a crucial step toward achieving this goal. It's like discovering a hidden spring in the desert, providing a source of relief and a more comfortable journey for those affected by OAB.

Dr. Camel's Conclusion

The desert of OAB research is vast, but this study illuminates a promising path forward. The exploration of new targets and therapies offers hope for a future where OAB can be managed more effectively and with fewer side effects, providing a more comfortable journey for all those affected by this condition.

Date :
  1. Date Completed 2007-07-23
  2. Date Revised 2019-09-17
Further Info :

Pubmed ID

17594185

DOI: Digital Object Identifier

10.1517/13543784.16.7.999

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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