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Critical periods of neuroendocrine development: effects of prenatal xenobiotics.

Author: DornL D, YaffeS J

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Prenatal phenobarbital exposure in animals has profound and permanent effects on reproductive function in offspring. Preliminary analysis of a cohort of adolescents exposed to phenobarbital in utero suggests similar long-term effects in humans.
Paper Details　
Original Abstract of the Article :
Phenobarbital, when administered prenatally in a small dose to animals, produced profound, and permanent effects on reproductive function in the offspring. Preliminary analysis of a unique cohort of adolescents who were exposed to phenobarbital in utero, suggests that long-term effects are also evid...See full text at original site
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引用元：
https://doi.org/10.1007/978-1-4684-8047-4_9

データ提供：米国国立医学図書館（NLM）

The Lasting Impact of Prenatal Xenobiotics on Neuroendocrine Development: A Journey Through Time

The journey of development is a delicate and complex one, like a delicate balance in the desert ecosystem. This study explores the impact of prenatal exposure to xenobiotics, specifically phenobarbital, on neuroendocrine development, highlighting the long-lasting effects of these substances on the offspring.

Examining the Long-Term Consequences of Prenatal Phenobarbital Exposure

The researchers investigated the effects of prenatal phenobarbital exposure on reproductive function in animal models and human populations. This is like observing the impact of a drought on the desert – understanding the long-term consequences of these exposures is crucial for protecting the health of future generations. Their findings suggest that prenatal phenobarbital exposure can have profound and lasting impacts on neuroendocrine development.

The Importance of Prenatal Care and Environmental Protection

This study serves as a reminder of the importance of prenatal care and environmental protection in safeguarding the health of future generations. This is like protecting a fragile oasis in the desert – we must be mindful of the substances that could harm the developing fetus. The research underscores the need to carefully consider the potential impacts of prenatal exposures on neuroendocrine development.

Dr.Camel's Conclusion

The desert of prenatal development is a complex and intricate one, where even small disturbances can have significant consequences. This research sheds light on the long-lasting effects of prenatal exposure to xenobiotics, like a ripple effect in a vast desert lake. It’s a call to action, urging us to prioritize the health and well-being of future generations by protecting them from harmful exposures and ensuring a healthy start to life.

Date :
  1. Date Completed 1992-03-10
  2. Date Revised 2019-06-22
Further Info :

Pubmed ID

1781340

DOI: Digital Object Identifier

10.1007/978-1-4684-8047-4_9

SNS
PICO Info
in preparation
Languages

English

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