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Effect of vitamin A and zinc supplementation on gastrointestinal parasitic infections among Mexican children.

Author: DuPontHerbert L, HertzmarkEllen, LongKurt Z, MontoyaYura, RosadoJorge L, SantosJose Ignacio, de Lourdes SolanoMaria

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Vitamin A and zinc supplementation had distinct effects on gastrointestinal parasite infections in young children. Vitamin A plus zinc reduced Giardia lamblia incidence, while zinc alone increased Ascaris lumbricoides incidence but decreased Entamoeba histolytica-associated diarrhea. These findings underscore the importance of parasite-specific interventions in addressing nutritional deficiencies and improving child health in developing countries.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: Gastrointestinal parasites continue to be an important cause of morbidity and stunting among children in developing countries. We evaluated the effect of vitamin A and zinc supplementation on infections by Giardia lamblia, Ascaris lumbricoides, and Entamoeba histolytica. METHODS: A rando...See full text at original site
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引用元：
https://doi.org/10.1542/peds.2006-2187

データ提供：米国国立医学図書館（NLM）

The Impact of Vitamin A and Zinc on Parasitic Infections

The fight against [gastrointestinal parasitic infections] is a global challenge, particularly in developing countries. This study examined the impact of [vitamin A and zinc supplementation] on the prevalence of [Giardia lamblia, Ascaris lumbricoides, and Entamoeba histolytica] in a cohort of [Mexican children]. The researchers conducted a [randomized, double-blind, placebo-controlled trial] and analyzed the [incidence and duration of infection] over a [one-year period].

Differential Effects of Vitamin A and Zinc

This study revealed [distinct parasite-specific effects of vitamin A and zinc supplementation]. While [vitamin A plus zinc] was associated with a [reduced incidence of Giardia lamblia infections], [zinc supplementation alone] resulted in an [increased incidence of Ascaris lumbricoides infections]. Interestingly, [zinc supplementation] also led to [longer durations of Entamoeba histolytica infections]. The findings emphasize the importance of [tailoring nutritional interventions] based on specific parasitic infections.

Nutritional Strategies for Parasitic Infections

Imagine a delicate ecosystem within the human gut, where various organisms compete for resources. This study delves into how [vitamin A and zinc] can influence this ecosystem, impacting the prevalence of [parasitic infections]. The research highlights the importance of [balanced nutrition] in maintaining a healthy gut environment, especially in vulnerable populations like children. By understanding these intricate relationships, we can develop more targeted nutritional strategies to address the challenges posed by [gastrointestinal parasitic infections].

Dr. Camel's Conclusion

This study is a reminder that even in the seemingly straightforward realm of nutrition, complexity exists. Just as a desert landscape can offer a variety of plants, each with its unique properties, so too can vitamins and minerals exhibit diverse effects. By understanding these nuances, we can develop more effective strategies to combat parasitic infections and ensure the health and well-being of individuals, particularly in communities facing these challenges.

Date :
  1. Date Completed 2007-10-29
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

17908741

DOI: Digital Object Identifier

10.1542/peds.2006-2187

Related Literature

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・Effective treatment of giardia infections
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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