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A parallel group randomised comparative study of felodipine and nifedipine in hypertension.
Author: AroraR, KaulU A, KhalilullahM, SethiK K, SharmaS M
Original Abstract of the Article :
We compared the antihypertensive effects and tolerability of a new calcium channel antagonist felodipine with nifedipine in an open randomised parallel group study in 49 patients with moderate hypertension (diastolic blood pressure 105-120 mm Hg). After two weeks run in period felodipine 5 mg and 10...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/1800302
データ提供:米国国立医学図書館(NLM)
Calcium Channel Blockers: Comparing Felodipine and Nifedipine in Hypertension
Hypertension, a silent killer that affects millions worldwide, requires effective and well-tolerated treatments. This study compares the antihypertensive effects and tolerability of two calcium channel blockers, felodipine and nifedipine, in patients with moderate hypertension. The study used a randomized, parallel group design, a method that randomly assigns participants to different treatment groups to ensure a fair comparison. The researchers found that felodipine was as effective as nifedipine in lowering blood pressure, but offered the advantage of once-daily dosing. While both drugs were associated with side effects, felodipine was generally better tolerated than nifedipine.
Felodipine: An Effective and Well-Tolerated Option for Hypertension
The study's findings suggest that felodipine is an effective and well-tolerated treatment option for moderate hypertension. While both felodipine and nifedipine showed similar reductions in blood pressure, felodipine's once-daily dosing regimen offers a convenience advantage for patients. Furthermore, felodipine was associated with fewer side effects and better tolerability compared to nifedipine. These findings highlight the potential of felodipine as a valuable treatment option for hypertension.
Managing Hypertension: A Multifaceted Approach
Managing hypertension is a journey through a vast desert of cardiovascular risk. This study provides valuable insights into the effectiveness and tolerability of different treatment options. It emphasizes the importance of considering factors such as efficacy, side effects, and dosing frequency when choosing the right treatment approach. In addition to medication, lifestyle modifications such as dietary changes, regular exercise, and stress management are crucial components of managing hypertension. Remember, a well-rounded approach, like a wise traveler in the desert, can lead to a healthier heart and a longer life.
Dr.Camel's Conclusion
This study demonstrates the effectiveness of felodipine as a treatment for hypertension. The study found that felodipine is as effective as nifedipine in lowering blood pressure and is better tolerated, making it a valuable option for patients with moderate hypertension.
Date :
- Date Completed 1992-04-23
- Date Revised 2013-11-21
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English
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