Oral naltrexone to enhance analgesia in patients receiving continuous intrathecal morphine for chronic pain: a randomized, double-blind, prospective pilot study.

Author: HamannScott, SloanPaul

Paper Details 
Original Abstract of the Article :
Years' worth of observations suggest that morphine has both inhibitory and excitatory actions, and that selective blockade of excitatory effects by low doses of opioid antagonists (e.g., naltrexone) may paradoxically enhance morphine analgesia. The purpose of this pilot study was to evaluate and com...See full text at original site
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引用元:
https://doi.org/10.5055/jom.2007.0051

データ提供:米国国立医学図書館(NLM)

Oral Naltrexone to Enhance Morphine Analgesia

Pain is a complex and challenging experience, often requiring a multi-faceted approach to management. This study explores the potential benefits of combining oral naltrexone with continuous intrathecal morphine infusions for the treatment of chronic pain. The research investigates whether this combination can enhance pain relief by selectively blocking the excitatory effects of morphine, potentially leading to a more effective analgesic effect.

A New Approach to Pain Management

The study delves into the intricate world of opioid analgesia, exploring the potential of a novel combination therapy for chronic pain. The researchers investigated whether combining oral naltrexone with intrathecal morphine could enhance analgesic efficacy and improve patient outcomes. The results suggest that this approach may be a promising strategy for managing chronic pain, offering a potential oasis of relief in the desert of discomfort.

A Holistic Approach to Pain Relief

The study's findings highlight the importance of a holistic approach to pain management. The researchers demonstrate that combining different therapies, such as oral naltrexone and intrathecal morphine, can lead to enhanced pain relief and improved patient outcomes. It's important to work with a qualified healthcare professional to develop a personalized treatment plan that addresses the unique needs of each individual experiencing chronic pain.

Dr.Camel's Conclusion

This research is like a camel caravan traversing a desert of pain, seeking to find new and effective treatment options. The study explores the potential benefits of combining oral naltrexone with intrathecal morphine, offering a novel approach to managing chronic pain. The findings suggest that this combination therapy could enhance analgesic efficacy and improve patient outcomes. It's a reminder that pain management is a complex and individualized process, and a holistic approach can lead to better results.

Date :
  1. Date Completed 2008-01-03
  2. Date Revised 2019-11-10
Further Info :

Pubmed ID

18027539

DOI: Digital Object Identifier

10.5055/jom.2007.0051

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English

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