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[Administration of ketamine during induction and maintenance of anaesthesia in postoperative pain prevention].

Author: ColombaniS, DixmériasF, GékièreJ-P, KabbaniY, LakdjaF, Mathoulin-PélissierS, MonninD

Clinical Trial, Phase IIIA Phase III trial is a trial that further rigorously verifies the efficacy and safety of a new drug or treatment, whose efficacy and safety have been confirmed in a Phase II trial, in a large number of patients, and evaluates whether it is superior to existing treatments.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Carcinologic breast surgery causes moderate postoperative pain and requires 30% more morphine. This study discusses the potential benefits of ketamine as an R-NMDA antagonist, administered peri-operatively, to reduce morphine use and its adverse effects.
Paper Details　
Original Abstract of the Article :
Carcinologic breast surgery is responsible of intermediary postoperative pain and needs 30% additional morphine. Now, morphine administration generates adverse effects. Publications about morphine saving effect of ketalar as antagonist of R-NMDA, administrated in perioperative increase are discussed...See full text at original site
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引用元：
https://doi.org/10.1016/j.annfar.2007.11.025

データ提供：米国国立医学図書館（NLM）

Ketamine: A Desert Oasis in Postoperative Pain Management

Breast surgery, a formidable challenge, often leaves patients facing a desolate landscape of postoperative pain. This study explores the potential of ketamine, a medication known for its analgesic properties, as a tool for mitigating this discomfort, akin to discovering a refreshing oasis in the midst of a scorching desert.

Ketamine: A Bridge Across the Painful Desert

The study suggests that ketamine, when administered during surgery, may offer a potential pathway towards reducing postoperative pain, a valuable bridge across the arduous desert of recovery. The authors highlight the benefits of ketamine in reducing the need for morphine, a medication that carries its own set of potential side effects, like a treacherous sandstorm in the desert.

Navigating the Desert of Postoperative Pain

This study opens up a new avenue for exploring effective pain management strategies, a crucial aspect of navigating the challenging landscape of postoperative recovery. The potential of ketamine to reduce pain and minimize opioid reliance offers a ray of hope for patients seeking a smoother journey through the desert of discomfort.

Dr.Camel's Conclusion

The desert of postoperative pain can be a daunting experience, leaving patients feeling parched and lost. This study offers a glimpse of hope, highlighting the potential of ketamine to alleviate suffering and provide a more comfortable recovery journey. Further research and clinical trials are essential to explore the full potential of ketamine, paving the way for a more peaceful and pain-free passage through this challenging landscape.

Date :
  1. Date Completed 2008-08-06
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

18272319

DOI: Digital Object Identifier

10.1016/j.annfar.2007.11.025

Related Literature

Article Analysis
・Effects of morphine
SNS
PICO Info
in preparation
Languages

French

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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