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Nevirapine-induced side effects in pregnant women: experience of a Brazilian university hospital.

Author: CarraroElaine Aparecida, CornelsenTaynah Cristina, DiasJosiane Mourão, KondoWilliam, MacedoRodolfo Lara de, PeriniJuliane, PrandelElaine, SasakiMaria das Graças, SbalquieroRenato

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Nevirapine, a medication used for HIV infection, can cause adverse events, including skin rash and liver function abnormalities, in pregnant women. The study found that 20.3% of pregnant women who started nevirapine during pregnancy experienced these adverse effects, with skin rash being the most common. There was no correlation between high CD4 counts and adverse events, but hepatotoxicity occurred only in women with CD4 counts ≥ 250 cells/µL.
Paper Details　
Original Abstract of the Article :
Nevirapine-based therapy is associated with increased frequency of adverse events among HIV-infected pregnant women. The aim of this article was to evaluate the incidence of adverse effects in HIV-infected women who started nevirapine during pregnancy. A retrospective study was performed in our cent...See full text at original site
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引用元：
https://doi.org/10.1590/s1413-86702007000600004

データ提供：米国国立医学図書館（NLM）

Nevirapine-Induced Side Effects in Pregnant Women: A Brazilian Study

HIV treatment during pregnancy is a complex issue, requiring careful consideration of both maternal and fetal health. This research investigates the incidence and characteristics of side effects associated with nevirapine, an antiretroviral medication, in pregnant women with HIV. The study found that nevirapine-induced side effects were common, primarily involving skin rash and liver function abnormalities. The authors highlight the importance of monitoring for these side effects and adjusting treatment strategies as needed to ensure patient safety.

Navigating the Challenges of HIV Treatment During Pregnancy

This research underscores the need for careful monitoring and management of HIV treatment during pregnancy. The study's findings highlight the importance of considering individual patient factors, potential risks, and the need for close follow-up to ensure optimal outcomes for both mother and child. It's a reminder that HIV treatment during pregnancy is a complex and delicate process requiring a multidisciplinary approach.

Prioritizing Maternal and Fetal Health

The health of both mother and child is paramount during pregnancy. This research emphasizes the importance of weighing the benefits and risks of different HIV treatment regimens, particularly during pregnancy. It's a reminder that healthcare providers must prioritize the well-being of both mother and child, ensuring that treatment decisions are made with careful consideration of all potential factors.

Dr. Camel's Conclusion

Just as a camel carefully navigates the desert to ensure its survival, healthcare providers must carefully manage HIV treatment during pregnancy to protect the health of both mother and child. This research sheds light on the potential side effects associated with nevirapine and emphasizes the importance of close monitoring and individualized care for pregnant women with HIV. It's a reminder that the journey towards a healthy pregnancy for women with HIV is a collaborative effort, requiring a team of healthcare providers and ongoing research to ensure optimal outcomes.
Date :
  1. Date Completed 2008-06-10
  2. Date Revised 2019-10-27
Further Info :

Pubmed ID

18327464

DOI: Digital Object Identifier

10.1590/s1413-86702007000600004

SNS
PICO Info
in preparation
Languages

English

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