Randomized, double-blind, placebo-controlled trial of probiotics for primary prevention: no clinical effects of Lactobacillus GG supplementation.

Author: HeinzmannAndrea, HennemuthIsabell, KoppMatthias Volkmar, UrbanekRadvan

Paper Details 
Original Abstract of the Article :
BACKGROUND: The value of probiotics for primary prevention is controversial. Published trials vary considerably in study design and the applied probiotics, thereby limiting comparability of the results. OBJECTIVE: The purpose of this trial was to study the preventive effect of the probiotic Lactoba...See full text at original site
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引用元:
https://doi.org/10.1542/peds.2007-1492

データ提供:米国国立医学図書館(NLM)

Probiotics: Not a Universal Solution for Atopic Dermatitis Prevention

The quest for effective ways to prevent atopic dermatitis, a common skin condition, continues to be a challenging journey. This study investigates the potential of Lactobacillus GG, a probiotic, to prevent the development of atopic dermatitis in infants. The double-blind, placebo-controlled trial, involving 105 pregnant women and their infants, found no significant difference in the incidence of atopic dermatitis between the probiotic and placebo groups. While the study did not support the use of Lactobacillus GG for atopic dermatitis prevention, it did highlight a potential association between probiotic supplementation and an increased risk of recurrent wheezing bronchitis. This finding underscores the need for further research to understand the complex interactions between probiotics, the immune system, and various health outcomes.

Probiotics: A Mixed Bag for Atopic Dermatitis

This study explores the potential benefits of probiotics in preventing atopic dermatitis, a common skin condition. The findings suggest that Lactobacillus GG, a specific probiotic, did not significantly reduce the incidence of atopic dermatitis in infants. However, the study also revealed a potential association between probiotic supplementation and an increased risk of recurrent wheezing bronchitis. This complex interplay between probiotics and health outcomes highlights the need for further research to better understand the role of probiotics in maintaining health and well-being.

Navigating the Desert of Atopic Dermatitis

This research highlights the complexity of atopic dermatitis and the need for a personalized approach to prevention and management. While probiotics may not be a universal solution for preventing atopic dermatitis, they may play a role in other aspects of health. It is essential to consult with a healthcare professional to discuss the potential benefits and risks of probiotic supplementation based on individual needs and medical history.

Dr.Camel's Conclusion

This research reminds us that the desert of health and well-being is a vast and complex landscape. While probiotics may not be a magic bullet for preventing atopic dermatitis, they could potentially influence other aspects of health. Further research is needed to fully understand the role of probiotics in maintaining overall well-being.

Date :
  1. Date Completed 2008-04-30
  2. Date Revised 2008-04-02
Further Info :

Pubmed ID

18332075

DOI: Digital Object Identifier

10.1542/peds.2007-1492

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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