Formulation and biopharmaceutical evaluation of transdermal patch containing benztropine.

Author: ChiSang-Cheol, HaiNguyen Thien, KimJuyoung, ParkEun-Seok

Paper Details 
Original Abstract of the Article :
Benztropine (BZ) is a potent muscarinic receptor antagonist that has been used for the treatment of Parkinson disease. However, the oral administration of BZ is often limited because of its many dose-related side effects. In this study, BZ was formulated into drug-in adhesive (DIA) patches in an att...See full text at original site
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引用元:
https://doi.org/10.1016/j.ijpharm.2008.01.024

データ提供:米国国立医学図書館(NLM)

Transdermal Benztropine Patches: A New Approach to Parkinson's Disease Treatment

Imagine Parkinson's disease as a desert landscape, where movement becomes increasingly difficult, like traversing a sandy terrain. This research explores a new approach to treating Parkinson's disease, using transdermal patches to deliver benztropine, a medication that helps alleviate symptoms.

The researchers developed transdermal patches containing benztropine, aiming to improve the delivery and effectiveness of this medication. They found that these patches effectively delivered benztropine to the skin, resulting in a significant bioavailability compared to oral administration. This research offers a promising new avenue for delivering benztropine, potentially offering improved treatment outcomes for those living with Parkinson's disease.

Transdermal Delivery: A New Frontier for Parkinson's Treatment

This research highlights the potential of transdermal drug delivery for treating Parkinson's disease. It suggests that this approach could offer several benefits, including improved patient compliance, reduced side effects, and potentially more effective treatment outcomes.

Understanding Parkinson's Disease

If you are living with Parkinson's disease, it's essential to consult with your healthcare provider to discuss the best treatment options for you. They can help you understand the different approaches available, including medication, therapy, and lifestyle modifications, and develop a personalized plan to manage your condition effectively.

Dr.Camel's Conclusion

This research showcases the innovative spirit of medical research, exploring new ways to deliver medications and improve treatment outcomes for individuals living with chronic conditions. It's a reminder that the quest for better healthcare solutions continues, driven by the dedication of scientists and healthcare professionals to enhance patient well-being.

Date :
  1. Date Completed 2008-08-25
  2. Date Revised 2016-11-24
Further Info :

Pubmed ID

18417307

DOI: Digital Object Identifier

10.1016/j.ijpharm.2008.01.024

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SNS
PICO Info
in preparation
Languages

English

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