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Efficacy, safety, and tolerability of desvenlafaxine 50 mg/day and 100 mg/day in outpatients with major depressive disorder.

Author: GangulyRita, LiebowitzMichael R, ManleyAmy L, PadmanabhanSudharshan K, TourianKaren A, TummalaRaj

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Desvenlafaxine 50 mg/day was associated with significantly greater improvement in Hamilton Rating Scale for Depression scores compared with placebo. Desvenlafaxine 100 mg/day was well-tolerated and demonstrated significant improvement on secondary efficacy measures.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To assess the efficacy, safety, and tolerability of 50- and 100-mg/day doses of desvenlafaxine (administered as desvenlafaxine succinate), a serotonin-norepinephrine reuptake inhibitor, for the treatment of major depressive disorder (MDD). RESEARCH DESIGN AND METHODS: Patients with Diagn...See full text at original site
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引用元：
https://doi.org/10.1185/03007990802161923

データ提供：米国国立医学図書館（NLM）
in preparation
Date :
  1. Date Completed 2008-08-11
  2. Date Revised 2022-03-21
Further Info :

Pubmed ID

18507895

DOI: Digital Object Identifier

10.1185/03007990802161923

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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