Monotherapy with nilutamide, a pure nonsteroidal antiandrogen, in untreated patients with metastatic carcinoma of the prostate. The Italian Prostatic Cancer Project.

Author: BoccardoF, CostantiniM, DecensiA U, GiulianiL, GuarneriD, MartoranaG, PaolettiM C, PositanoN

Paper Details 
Original Abstract of the Article :
A total of 26 previously untreated patients with metastatic carcinoma of the prostate received the pure nonsteroidal antiandrogen nilutamide as a single agent. Objective response rate was 38.5 +/- 18.7% (95% confidence interval). Median progression-free survival and median survival were 9 and 23 mon...See full text at original site
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引用元:
https://doi.org/10.1016/s0022-5347(17)37799-6

データ提供:米国国立医学図書館(NLM)

Nilutamide: A New Weapon in the Fight Against Prostate Cancer

[Prostate cancer] is a significant health concern, and finding effective treatments is a constant battle. This study investigates the use of [nilutamide], a nonsteroidal antiandrogen, as a single-agent treatment for patients with [metastatic carcinoma of the prostate]. The researchers found that nilutamide had a moderate activity, with an objective response rate of 38.5%.

Nilutamide Shows Promise for Treating Prostate Cancer

The study found that nilutamide had a [median progression-free survival] of 9 months and a [median survival] of 23 months. This promising result suggests that nilutamide could be a viable treatment option for patients with metastatic prostate cancer.

Navigating the Side Effects of Nilutamide

While nilutamide shows promise, it's important to consider its potential side effects, such as decreased adaptation to darkness, nausea, and alcohol intolerance. This is like navigating a desert at night, where it's essential to be aware of the challenges ahead. However, the researchers found that these side effects were generally mild and reversible upon cessation of treatment.

Dr.Camel's Conclusion

This study offers encouraging results for nilutamide as a treatment option for prostate cancer. It's important to weigh the potential benefits against the possible side effects and to discuss treatment options with a healthcare professional. The journey of fighting prostate cancer can be challenging, but with careful research and personalized care, we can find our way toward a healthier future.

Date :
  1. Date Completed 1991-08-29
  2. Date Revised 2019-06-21
Further Info :

Pubmed ID

1856935

DOI: Digital Object Identifier

10.1016/s0022-5347(17)37799-6

Related Literature

SNS
PICO Info
in preparation
Languages

English

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