The Procalcitonin And Survival Study (PASS) - a randomised multi-center investigator-initiated trial to investigate whether daily measurements biomarker Procalcitonin and pro-active diagnostic and therapeutic responses to abnormal Procalcitonin levels, can improve survival in intensive care unit patients. Calculated sample size (target population): 1000 patients.

Author: AndersenLasse H, AndersenMads H, BestleMorten, BømlerBonnie, CarlPeder, FjeldborgPaul, GrarupJesper, HeinLars, HestadSøren, HougaardSine, JensenJens-Ulrik, KjaerJesper, LarsenKim M, LauritsenAnne O, LundgrenBettina, LundgrenJens D, LøkenJesper, MantoniTeit, MohrThomas, OstergaardChristian, PetersenJ Asger, PetersenPernille L, RossauCharlotte, SteensenMorten, Søe-JensenPeter, ThomsenCarsten B, ThormarKatrin, ThornbergKlaus J, TousiHamid

Paper Details 
Original Abstract of the Article :
Sepsis and complications to sepsis are major causes of mortality in critically ill patients. Rapid treatment of sepsis is of crucial importance for survival of patients. The infectious status of the critically ill patient is often difficult to assess because symptoms cannot be expressed and signs ma...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2491622/

データ提供:米国国立医学図書館(NLM)

Procalcitonin: A Potential Game-Changer for Sepsis Management

This research focuses on sepsis, a serious and potentially life-threatening condition caused by the body's overwhelming response to infection. This study explores the potential of procalcitonin (PCT), a biomarker that can indicate bacterial infection, as a tool to improve survival rates in critically ill patients. This research is like a camel caravan seeking a new oasis, searching for a reliable marker to guide the diagnosis and treatment of sepsis. The study proposes a randomized controlled trial to investigate whether daily PCT measurements and proactive therapeutic responses based on abnormal PCT levels can lead to improved survival outcomes for patients in intensive care units. This research is like a camel caravan carefully planning its journey, aiming to optimize treatment strategies for critically ill patients with sepsis.

Procalcitonin: A Beacon in the Storm

The study's proposal highlights the potential of PCT as a valuable tool for diagnosing and managing sepsis. This research is like a camel caravan discovering a new source of water in the desert, offering a promising tool for navigating the complexities of sepsis treatment. The study suggests that using PCT as a guide for treatment decisions could improve outcomes for critically ill patients, potentially leading to reduced mortality and morbidity.

Navigating Sepsis: Early Detection and Intervention

Early detection and prompt treatment are critical for improving outcomes in sepsis. This research, like a camel caravan navigating treacherous terrain, emphasizes the importance of early intervention in critical illness. The study's proposal suggests that using PCT as a guide could lead to more timely and effective interventions, potentially improving survival rates for patients with sepsis. Remember, just as a camel relies on its keen senses to navigate the desert, early detection and appropriate interventions are essential for managing critical illness.

Dr. Camel's Conclusion

This study, like a camel caravan seeking a path through the desert, aims to explore the potential of procalcitonin as a crucial tool for improving sepsis management. The research suggests that using PCT as a guide for diagnosis and treatment decisions could lead to earlier interventions and potentially better outcomes for critically ill patients. Just as a camel relies on its instincts to navigate the harsh desert, prompt action and effective treatment are essential for overcoming the challenges of sepsis.

Date :
  1. Date Completed 2008-11-18
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

18620598

DOI: Digital Object Identifier

PMC2491622

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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