Interferon-beta1b for the treatment of multiple sclerosis.

Author: GottesmanMalcolm, LamSum, WangShan

Paper Details 
Original Abstract of the Article :
BACKGROUND: Multiple sclerosis is a debilitating autoimmune disorder that causes disability in young adults. OBJECTIVE: To review the efficacy and safety of IFN-beta1b in the management of relapsing-remitting and secondary progressive multiple scleroses and clinical isolated syndrome. METHODS: A M...See full text at original site
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引用元:
https://doi.org/10.1517/17425255.4.8.1111

データ提供:米国国立医学図書館(NLM)

Interferon-beta1b for Multiple Sclerosis: A Treatment Review

Multiple sclerosis (MS) is a debilitating autoimmune disorder that affects the central nervous system. This review examines the effectiveness and safety of interferon-beta1b as a treatment for MS, including relapsing-remitting MS, secondary progressive MS, and clinical isolated syndrome.

Interferon-beta1b's Efficacy and Safety

The review concluded that interferon-beta1b is more effective than a placebo and at least as effective as other treatments for relapsing-remitting MS, such as interferon-beta1a and glatiramer. It also found that interferon-beta1b can delay the diagnosis of definite MS and reduce brain lesion burden in patients with clinical isolated syndrome. However, the authors acknowledged that more long-term and large-scale clinical data are needed to fully assess its relative effectiveness compared to other treatments. Common side effects of interferon-beta1b include lymphopenia, injection site reactions, asthenia, flu-like symptoms, and headache.

Implications for MS Treatment

This comprehensive review, like a map guiding travelers through the complexities of MS, provides valuable insights into the efficacy and safety of interferon-beta1b. While it is a potentially effective treatment, it is crucial to weigh its benefits against potential risks and to monitor patients for side effects.

Dr.Camel's Conclusion

This research, like a steady camel caravan carrying a precious cargo of knowledge across the vast desert of MS, offers important information for patients and their physicians. While interferon-beta1b may be a valuable tool in the treatment of MS, it is essential to approach its use with a careful and informed perspective, considering both its potential benefits and risks.

Date :
  1. Date Completed 2008-12-11
  2. Date Revised 2019-11-11
Further Info :

Pubmed ID

18680445

DOI: Digital Object Identifier

10.1517/17425255.4.8.1111

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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