Influence of polymorphic N-acetyltransferases on non-malignant spontaneous disorders and on response to drugs.

Author: LaderoJ M

Paper Details 
Original Abstract of the Article :
Polymorphic N-acetyl transferases (NAT) 1 and 2 are involved in detoxification of xenobiotic arylamines and hydralazines. These common environmental chemicals may be related to the pathogenesis of many spontaneous disorders, mainly malignancies, but also disimmune or degenerative diseases, for which...See full text at original site
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引用元:
https://doi.org/10.2174/138920008784892038

データ提供:米国国立医学図書館(NLM)

Unraveling the Influence of N-Acetyltransferases on Human Health

The field of [pharmacogenetics] explores the role of [genetic variation] in influencing [drug response] and [disease susceptibility]. This research delves into the [polymorphic N-acetyltransferases (NATs)], enzymes involved in [detoxification] of various compounds. The authors investigated the potential association between [NAT polymorphisms] and a range of [non-malignant spontaneous disorders] as well as [drug responses].

NAT Polymorphisms: A Potential Factor in Disease Risk

The study suggests that [NAT2 polymorphism] may be associated with an increased risk of developing certain [non-malignant disorders], although further research is needed to confirm these findings. The authors also highlight the importance of [NAT2 genotype] in predicting [drug response] and [side effect] profiles.

Personalized Medicine: The Future of Healthcare

This research underscores the growing importance of [personalized medicine]. By understanding the [individual genetic variations] that influence [drug metabolism] and [disease risk], clinicians can tailor treatment strategies for optimal outcomes and minimize the risk of [adverse reactions]. As we move towards a more personalized approach to healthcare, understanding the role of [NAT polymorphisms] is a crucial step.

Dr.Camel's Conclusion

Just as the desert sands shift and change over time, so too does our understanding of the human genome. This research highlights the dynamic interplay between [genetics] and [health], emphasizing the importance of [personalized medicine]. By deciphering the intricate patterns of [NAT polymorphisms], we can better understand individual susceptibility to [disease] and optimize [drug therapy]. This research is a reminder that the journey of medical discovery is a constant exploration, much like a camel traversing the ever-changing desert landscape.

Date :
  1. Date Completed 2008-09-25
  2. Date Revised 2019-10-27
Further Info :

Pubmed ID

18680473

DOI: Digital Object Identifier

10.2174/138920008784892038

Related Literature

SNS
PICO Info
in preparation
Languages

English

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