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[Effect of apomorphine injection into the nucleus accumbens on the limb preference in manipulation movements in rats].

Author: BudilinS Iu, IoffeM E, MidzianovskaiaI S, PasikovaN V

English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study explores the possibility of changing handedness in rats by injecting a dopamine agonist, apomorphine, into the nucleus accumbens. Chronic injection of apomorphine significantly altered limb preference.
Paper Details　
Original Abstract of the Article :
The concentration of dophamine and its derivates is known to correlate with the degree of handedness in manipulative movements in rodents. In this work we studied a possibility to changing handedness in rats by injection of a dopamine agonist into the nucleus accumbens. Retrieving food from a horizo...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/18689245

データ提供：米国国立医学図書館（NLM）

Investigating the Link Between Dopamine and Handedness in Rats

This study delves into the fascinating world of neuroscience, exploring the potential connection between dopamine, a neurotransmitter, and handedness in rats. The researchers examined the impact of injecting apomorphine, a dopamine agonist, into the nucleus accumbens, a brain region associated with reward and motivation, on limb preference in rats. They found that chronic injection of apomorphine significantly altered limb preference, suggesting a potential role for dopamine in shaping handedness.

Dopamine Plays a Role in Shaping Handedness

The study suggests that dopamine plays a significant role in determining limb preference. This finding opens up new avenues for understanding the neural mechanisms underlying handedness and potentially exploring the role of dopamine in other aspects of motor control.

Health and Lifestyle Implications

While this study focuses on animal models, the findings may have implications for understanding handedness in humans. It's important to note that handedness is a complex trait influenced by multiple factors, including genetics and environmental influences.

Dr. Camel's Conclusion

This study reveals the intricate relationship between dopamine and handedness. It emphasizes the importance of further research to understand the complexities of motor control and the role of neurotransmitters in shaping behavior. As a researcher, I find this study intriguing because it underscores the potential for exploring the brain's inner workings and unraveling the mysteries of complex human behaviors.
Date :
  1. Date Completed 2008-10-10
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

18689245

DOI: Digital Object Identifier

18689245

Related Literature

Article Analysis
・Effects of apomorphine injection
SNS
PICO Info
in preparation
Languages

Russian

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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